Pancytopenia - boemong pathological oo decreases maling e potoloha ea likarolo tsohle tsa ea ho hlophisoa. Sesosa, matšoao, kalafo

Leha e le ntshetsopele ya lefu ka 'mele o e etsa hore ho fetola tshebetso ho tloha maling pheriferale. Leha ho le joalo, ho na le a 'maloa a pathologies eo liphetoho tse joalo ke tse ka sehloohong tsa tleleniki tšobotsi. Pancytopenia - ke e nngwe ya dithulaganyo pathological ba tsamaiso hematopoietic, e leng e hlalosoa e le lefu le le ikemetseng, kapa a ka ba le ponahalo ea ba bang pataganeng nosological.

bopa dikgopolo tsa kakaretso

Lefu lena le ke se se sa tlwaelesegang, kahoo batho ba bangata ba sa tsebe hore na ka ketsahalo e joalo. Pancytopenia - boemo ba khaello ea lisele tsa mali, ntshetsopele ya eo ho bakoa ke tsela e sa tloaelehang ka sebōpeho sa lisele tse selelekela mali ka ho ba sethaleng sa hematopoiesis. Fokotswa maemo tsa lisele tse khubelu tsa mali, lisele tse tšoeu tsa mali le liplatelete e loketseng ha e le hantle hore lisele tse bakoang ke ke ho lekaneng ho sebetsa.

Lefu lena le hlaha ka mefuta e 'meli:

• idiopathic, bakoang ke mabaka a ka hare;
• mahareng, e leng e etsa hore ke tšusumetso kantle.

A boemong bo pathological e ka bang ka 50% ea linyeoe develops autoimmune mofuta. Ke hore, 'mele o e loana le mong le lisele tsa mali hao, tswalanye ka pho so bona bakeng sa mahlahana a tsoang linaheng tse ling. foromo Idiopathic ka hlaha khahlanong le kamano ya tlatsetso Ntlha e Link hore eketsa sephetho boima.

Pancytopenia - lefu le hore a ka ho futsitseng, ho ntshetsa pele ka nako ea ha lesea e ka pōpelong. ngoana e e hlahile se le maloetse a sa litho tsa mali-eaba ba etsa. Ho ka ba congenital le masapo moko hypoplasia, e le hore tsamaiso ke ke sebetsana ka katleho le mesebetsi ea bona.

The etiology tsa lefu le kotsi le lintlha

Har'a lisosa tse ka sehloohong ea tsoelo-pele ea lefu ba liphetoho liphatseng tsa lefutso bo liphatseng tsa lefutso, ho sebelisa nako e telele ea lithethefatsi, ntšang mahlaseli a kotsi kapa litla nang le chefo e. foromo Idiopathic e tšoauoa ka 'nete ea hore na sesosa ke sefe ke ke ho thehwa, Leha ho le joalo, ho ne ho maemo a ho lefu la mora bana.

Theha mabaka a ke habohlokoa hore le phello e ntle. Felisa Link mpe tšusumetso e ka lefu lena - 50% sekhahla katleho.

Ho phaella ho le mabaka a ka sehloohong ho na le lintho tse 'maloa e tlatsetsang ho ntshetsopele ya bolwetse ba:

• Sebetsa le benzene kapa arsenic;
• Fanconi khaello ea mali;
• mofuta bongata ba kokwanahloko ea tšoaetso ea;
• chemotherapy khafetsa;
• lithibela-mafu le ho immunosuppressants;
• mafu autoimmune kang systemic lupus erythematosus;
• radiotherapy.

Fanconi khaello ea mali - e mong oa mabaka a etiological tsa pancytopenia. Develops ka semelo sa anomalies congenital e nkoa e le autosomal recessive lefu. Khaello ea mali e tšoauoa ka ho ba teng ha ka likoli ka likarolo tse ling tsa liprotheine le boikarabelo ba ho DNA ho lokisa le chromosome friability.

The litleleniki tsa setšoantšo sa lefu lena

boemo Pathological bontša ka boeona e ka mokgwa wa syndromes tse tharo. E mong le e litšobotsi tsena bath ho fokotsa palo ea mofuta 'ngoe ea lisele tsa mali. Leukopenia ho bontšoa setšoantšo sa sepsis a hlobaetsang le ho hlaha ha dithulaganyo seso-necrotic tsa letlalo le lera la mucous.

Erythropenia le tshwaileng e fokotseha ha haemoglobin qholotsa ntshetsopele ya matšoao a khaello ea mali. boemong bona e tšoauoa ka:

• paleness tsa letlalo integument;
• fofelang pel'a mahlo a hae ;
• ho tsekela;
• tinnitus;
• bofokoli le mokhathala;
• bofokoli.

Bakuli ba tletleba ba bokhutšoanyane phefumoloho le pelo palpitations. Auscultation ho bona hore melumo voiceless pelo, systolic korotlela holim eohle ea boqapi ba pelo, molumo oa tlhōrōng ea mothapo jugular. A ntseng a mpefala boemo ba mokuli baka liphetoho electrocardiogram, e leng bontša tsoelo-pele ea ha pelo.

Thrombocytopenia e bontšoa ke khafetsa tsoa mali (epistaxis, gastrointestinal, uterine), tsoa mali marenene, ponahalo ea petechiae le hemorrhages letlalong. matšoao a hlobaetsang le lefu lena a 'na a hoo e ka bang khoeli' me hangata isa lefung. Foleng pancytopenia lumelloa molemo ka ho eketsehileng 'me o na le matšoao a ka tlaase ho moo phatlalletsoang

le lefu lena e nkoa e le bakeng sa ho e rarahaneng haholo. Pancytopenia, eo mathata a ho feta ho tloaelehile hore batho ba hōlileng, a tsamaea le ponahalo ea tšoaetso ea le mali.

mehato tekotshupo

Tabeng ea pele hloka fetisetsa ho hlahloba ngaka, histori pokello le bophelo ba mokuli. Ho ekelletsa moo a khethoa CBC. Tabeng ea litsupa tsena ka nahana ka tsoelo-pele ea pancytopenia le tsamaisa mehato ka ho eketsehileng tekotshupo:

• leukocytes <2: x 109 / k;
• liplatelete <150: x 109 / L;
• erythrocytes <3,5: x 109 / k.

Abeloa ho ithuta puncture lesapo moko, e hlalosang mantsoe e hlalosa ho ba teng ha lisele tse sa tloaelehang le myelokaryocytes. E behilweng ke ho ba teng ha e sa tloaelehang, ho akarelletsa lesapo moko hypoplasia. Hape e neng e tšoaretsoe disampole haemolytic.

pancytopenia kalafo

mehato phekolo e itšetlehile ka tabeng ea tleleniki, boemo ba mokuli le palokatiso etiological e bakileng lefu lena. Latelang kalafo mekhoa e ka sebediswa:

• Tšeloa mali, ho leka-lekanya ka tekano likarolo foromo.
• Transplantation ea lesapo moko kapa bakoang liseleng. Hangata e etsoa ka bakuli ba bacha le ba mahareng lilemo.
• Tabeng ea pancytopenia autoimmune laolwa kopo immunosuppressant "Cytoxan", "Methylprednisolone," "Neoral", "Sandimun".
• Ho bolela Stimulating le lesapo moko ho sebetsa - "Neupogen", "Neulasta", "Procrit", "Leukin".

dimela lithethefatsi

E rarahaneng lefu phekolo e akarelletsa ho sebelisoa ha ho phekola ka litlama. Boemo ba lisele tse khubelu tsa mali le haemoglobin ka tsosoa ka thuso ea monokotsoai. teas e etselitsoeng liqhobosheane tse entsoeng ka lebaka la molora, currants ntšo, a ema letheka, fragole, frutos e, apricot. Tšepe morui, tse bonesitsoeng ka, gooseberries, cherries le morara, ho ja e neng e tla se feela leka-lekanya le ho leka-lekana ea lisele tsa mali, empa hape ho matlafatsa boitshireletso ba mmele.

ba bangata ba mekhoa e setso bakeng sa ho phekola pancytopenia kenyelletsa ditokiseletso mahe a linotši. E ho kopantswe le lihlahisoa tse latelang:

• le veine e khubelu 'me a lekhala;
• konofolo;
• habore;
• lemon, apricots omisitsoeng, morara o omisitsoeng, faolang le walnuts.

Hokela le habohlokoa haholo ho infusions le decoctions ea meriana ea litlama bobatsi bobatsi, birch, joang Sage, clover, dandelion, orchid e, clover, buckwheat.

bofello

Pancytopenia - le ho kula haholo, o bontšang hore lefu le bolaeang. Tšoanelang sephetho itšetlehile ka ho tiea tsa matšoao tlelenike, liforomo le mekhahlelo ea ho hōla ka ho eo kalafo qala. lefu joalo ke ho le bonolo ho thibela ho feta ho pheko.

La bongaka ba ngotse hlahlobo ya selemo le selemo ea baahi ba thusa hore boitsebahatso ba boemong pathological ka mekhahlelo ba pele. Ka ho khetheha ena e sebetsa ho mekhoa laboratori ea hlahloba.