Eketseha lymphocytes maling: mabaka a ho ho tlhaloseditswe ke

Lisele tse ea tsamaiso ea batho boitshireletso - lymphocytes - ho matleng a sehlopha leukocyte tsa agranulocytes tšoeu le ho etsa maemo bakeng sa sebopeho sa maloetseng humoral le lisele. maloetseng Humoral develops lisireletsi le sele e fana ka kopana le lisele tse mahlatsipa. lymphocytes hape sebetsa e le bashebelli ba liseleng tse ling mali le ho laola mesebetsi ea bona, ha ho hlokahala.

Lymphocytes le lymphoblasts

Lymphocytes - e laola likarolo lisele tsa tsamaiso eohle boitshireletso ka 'mele oa motho, e leng kena mali ho tswa ho moko lesapo ebe sebetsa ka mafolo-folo ka lymphoid dinama tse nyenyane tse. Haeba e ile ea eketseha lymphocytes maling, mabaka a bakeng sa ya tlhokeho e potlakileng tlhakiso, 'me ho hlokahale pele ba ho etsa tlhahlobo ea laboratori tloaelehileng. Ka batho ba baholo le litlaleho tse mali lymphocyte karoloana ya 20 - karolo ea 35 lekholong ea palo ea lisele tse tšoeu. Ba bang ba bona (ka 2%) ke ka ho mahala ajoa ka phallo ea mali pheriferale, 'me 98% ka lisele tse ka. Ho ea ka lona lymphocytes morphological litšobotsi tse ba arotsoe ka lihlopha tse peli: e kholo granular (nk, lisele tse immunoblast, lymphoblasts) le tse nyenyane (T-lisele le B-lisele tse). All ea lisele tsena ba mafolofolo le lymphoblasts ameha dithulaganyo boitshireletso haholo ka tlaase ho moo. Ha o sheba dikahare tse phahameng tsa lymphocytes ka mali, e leng ho bolela hore 'mele ea liphetoho mpe li etsahala, ho ne ho e-ba mohloli a patiloeng a tshwaetso kapa ho ruruha ea moo.

lymphocyte sehlopha

lisele tse B lemoha antigens sebopeho mojaki phunyeletsang ka 'mele. Ka nako e tšoanang ba hlahisa limolek'hule le protheine e kokobetsa ho mahlahana a kotsi. T-lisele tse ho timetsa antigens lula maloetseng ka mohato ba mafolofolo, ho thibela khoehla lona. Eketseha lymphocytes maling, mabaka a sechaba sena ka 'na sa tsebe, ba lemoha ke teko ea mali. Nk, lymphocytes laola boleng ea lisele ho pholletsa le 'mele. Ka nako e tšoanang ba timetsa lisele, bao e seng ho latelwa, tse kang lisele tse kankere. T lymphocytes etsa 70-80% ea palo ea B-lisele tse di ka karo-karolelano ea 15-20%, 'me lymphocytes nk, fetisisa numerically nyenyane, dikahare tsa bona ha se ho feta 5-10%. Haeba e ile ea eketseha lymphocytes maling, mabaka a ka 'na ba e fapaneng, empa haeba leha e le efe e le pontšo eo' mele hase bohle le letona.

pathogenesis

Lymphocytes hammoho dikarolo bona limolek'hule thusa ho kenya tshebetsong le pathogenesis la khaello boitshireletso, mafu a tšoaetsanoang, kankere le mafu a alejiki, likhohlano transplant le, motuya koleka, ke lefu le autoimmune. Nakong ea opereishene ka 'na eketsa boemo ba lymphocytes' me ponahalo ea lymphocytosis, sena le hlaha ka e-ba le karabelo e lekaneng ho mosebetsi antigenic. Mohlomong ho na le ea eketseha palo ya lymphocytes, ho bolela ho qaleha ha loana lisele tse le antigens. Empa ho ka boetse tla boemo ba fokotseha, tabeng ea ka karabelo sa tšoanelehe ho tlhotlheletso le antigens ebe ho na le lymphopenia.

phetoho ea lymphocytes

Ikatisetsa litleleniki tsa, ho leukemoid itšoara joang lymphatic mofuta, eo ho eona ho na le mohlala ka litšobotsi tsa kankere ea mali a sa foleng kapa a hlobaetsang. liphetoho tse joalo li ka mononucleosis tšoaetsanoang, lefuba, mokaola le brucellosis. Tšoaetsanoang mononucleosis - ka lebaka la ho ba le tshwaetso ya bongata ba kokwanahloko, fetisisa ka tloaelo le hlaha ka bana, tšoauoa ka boemo bo phahameng ba leukocytosis ka lebaka la ho lymphocytes, tseo ka tsela ea lefu lena le fumana litsobotsi life tse ntjha ya ho fapafapana morphological. mali e ntlafatsa le lymphocytes atypical, ka lipontšo tsa dysplasia khubu le eketseha cytoplasm. Leha ho le joalo, ha fumanoa hore o tšoeroe ke eketseha lymphocytes maling, bakang tla tsejoa 'me felisoa ho ea fihla kamoo ho ka khonehang.