Allopurinol, ho rupela ho sesupo sa, litekanyetso li behoa, litla-morao 'me contraindications

"Allopurinol", thuto totobatsa lokolloa ka mokgwa wa matlapa a 100 mg,. Ho bua ka meriana ea lithethefatsi protivopodagricakih bolela thibela ho tswakana ea acid e uric. Ho ea ka sebōpeho "allopurinol" e ke analoge tsa hypoxanthine, inhibitory kgolo potlakisang tsebetso ea lik'hemik'hale tse kopanelang papaling ea ho ea sebopeho sa acid e uric. Lithethefatsi "allopurinol" ulasan pelanggan netefatsa e ama ho shoa hoa letsoai uric acid e, ka qetello ea thuto ea bona ea lisele tsa 'mele' me ka liphio.

"Allopurinol" taeo ho bopaki

moriana e hlophisitsweng:
bakeng sa ho thibela, ho phekola gout le hyperuricemia (ho akarelletsa le ho hloleha rarahaneng renal) hlahloba nephrolithiasis ,, urate nephropathy;
ka majoe k'halsiamo oxalate liphio hammoho le hyperuricosuria;
ka phahameng urate boemong ba, thehoa ka lebaka la mafu a enzymatic;
bakeng sa thibelo ea mafu a hlobaetsang nephropathy nakong cytostatic, mahlaseli a kalafo ya hlahala le kankere ea mali;
ha ya kalafi tlala.

"Allopurinol" taeo ho dosing ho

ngaka beha lethal dose ya lithethefatsi tse e motheo oa motho ho itšetlehile ka
boemo ba urate lemoha ka mali le ho moroto, hammoho le ka ea mahloriso ya acid e uric. Batho ba baholo le beha 100 mg, "Allopurinol" ho fihlela ho 900 mg, ka ho ya ka letsatsi. Letsatsi le letsatsi lethal dose e hlokahalang ea ho arola ka tekanyetso 2-4. matlapa a lokela ho ho nkoa ka ka mor'a lijo.
Bana ba ka tlaase ho lilemo tse 15 lethal dose ea letsatsi balwa ka ho nepahala ho ea ka moralo o balletsweng e: 10-20 mg, ka ho ya ka tse 1 kg 'mele oa boima ba' mele oa ngoana kapa laolwa 100 mg, "Allopurinol" ho 400 mg,.

The lethal dose lebetsoeng le bakeng sa bakuli ba litsebeng mosebetsi a liphio ke 100 mg,. ngaka e ka eketsa lethal dose ea ha semelo sa kalafo ea sala sa fetohe phahameng boemo ba urate fumanoa mali le moroto.

"Allopurinol" tataiso ho litla-morao

Maemong a sa tloaelehang, re hlokometse irregularities tsamaisong ea pelo, e leng o ile a bontša kgatelelo ya madi, bradycardia.
irregularities khoneha tsamaisong ea tshilong ya dijo tse bontšitsoeng:
ho nyekoa ke pelo, ho hlatsa, letshollo, e fetang eketseha transaminases hlokometse ka serum ka;
lefu la sebete, sebete ho se sebetse;
stomatitis (bakuli motho);
steatorrhea.

Maemong a ka thōko "Allopurinol" moriana o ile a etsa hore mafu a ka tsamaiso ea methapo, e leng ba bontša:
bofokoli, mokhathala, ho tšoaroa ke hlooho, molikoalikoane;
ataxia, boroko, ho tepella maikutlo;
coma, paresis, paresthesia;
cramps, neuropathy;
bonwang kholofalo; lera;
liphetoho tse ka sebopeho sa papilla optic;
dysgeusia.
seoelo haholo o ile a re irregularities tsamaisong ea hematopoietic hore li bonahatsoa ke thrombocytopenia, agranulocytosis le aplastic khaello ea mali, leukopenia (kotsi sehlopheng se akarelletsa bakuli ba fokotseha mosebetsi renal).

irregularities khoneha tsamaisong ea mosese, e leng ka seoelo interstitial nephritis; bakuli motho - edema, uremia, hematuria.

Meferefere tsamaisong endocrine etsahala maemong a sa tloaelehang, ho kgaolela basadi thari, ho hloka matla, gynecomastia, lefu la tsoekere.
mafu a tshilong ya dijo ka bonahala Maemong a seng makae hyperlipidemia.
Alejiki kapa dermatological bohloko liphetoho.

"Allopurinol" taeo ho contraindications ho

Ho ke ke ha khoneha ho hlalosa lithethefatsi:
ka mafu a ea sebete, a liphio;
Boimana le diabolololo;
tabeng ea hypersensitivity ho "Allopurinol".

Ikatisetsa tlelenike, bana ba ka tlase ho dilemo tse 12 tsa lilemo, "Allopurinol" balletsweng feela bakeng sa kalafo ya lihlahala tse kotsi, ka kankere ea mali, ha mafu a potlakisang tsebetso ea lik'hemik'hale, tse kang lefu Lesch-Nihena.