Thyroxine le triiodothyronine ba tsa maiketsetso ka lebaka la seo? Thyroid li-hormone - thyroxine le triiodothyronine

hormone thyroid li hlahisoang ke ho thyroid tsoelesa (SHCHZ). Thyroxine le triiodothyronine - tse peli tse ka sehloohong-hormone ea 'mele, le karolo ea eo ho eona ho ke iodine litareng athomo. hormone tsena li hlahisoang ke lisele tse sa epithelium follicular.

Karolo e phethoang ke li-hormone thyroid

Thyroxine le triiodothyronine tsa maiketsetso tloha tyrosine (acid e, alpha-amino) le ke tsa bohlokoa bakeng sa ntshetsopele tlwaelehileng tsa phelang.

• Tšehetsa mosebetsi oa setsi sa ho hema.
• Ka ho ba le seabo bona, o ile a laola molokong o mong ka mocheso ke 'mele.
• Ama metabolism oksijene 'me e ile ea eketseha tlhokeho dinama tse nyenyane tse ea oksijene.
• Ama matla a pelehi pelo (ionotropic e le hantle).
• Laola lebelo leo pelo (chronotropic e le hantle).
• Ka lebaka thyroid li-hormone e ntseng e eketseha palo ya receptors e b-adrenergic pelong le ya marapo mesifa, 'me tsa boela tsa hlophisa ka dinama tse nyenyane tse adipose le lymphocytes.
• Ebe o kenya tshebetsong le motility la pampitšana gastrointestinal.
• Tlas'a tšusumetso ea tswakana liprotheine tse fapa-fapaneng mehaho le dinama tse nyenyane tse ho khethollo ea.
• Susumelletsa ho ntshetsa pele le khōlo ea 'mele kaofela.
• Di hlohleletsago bohareng tsamaiso ea methapo tshebetso le potlakisa mokhatlo kelello.
• Laola mali tsoekere le eketsa nkhape le tshebediso ya lisele tse lona, ka tsela eo activating tshebetso ya ho glycolysis.
• Ama disintegration ea dinama tse nyenyane tse adipose (lipolysis) le lieha sebopeho sa eona 'me deposition.

Lokelang secretion hormone thyroid ka 'mele oa motho ho ka etsa hore tsoarelloa ntshetsopeleng kelellong le' meleng.

hormone tswakana SHCHZ

SHCHZ mantlha protheine e thyroglobulin. E sebeletsa e le thempleite bakeng sa sebopeho sa li-hormone tse hlahisoang ke tšoelesa e. Thyroxine le triiodothyronine ba tsa maiketsetso ka lebaka la thyroglobulin protheine. protheine ena e na le ka sebopeho sa eona sa fetang 5 likete amino acid e litlhaka kahare., 'me tse 18 tsa tsona feela tse iodized. Thyroxine e tsa maiketsetso le ho kenya letsoho ha litlhaka kahare amino acid e feela 2 ho 4. Ho phaella ho thyroglobulin, bakeng sa li-hormone SHCHZ kopanelang papaling le k'holeseterole e. Kahoo, thyroxine le triiodothyronine ba tsa maiketsetso ka lebaka la k'holeseterole, hammoho le li-hormone steroid. Thyroid li-hormone T4 o entsoe makhetlo a 10 ho feta T3 e.

Hormone Triiodothyronine (T3) Ho thehoa ke e kopana le limolek'hule di- le monoiodotyrosine hore ke karolo ea protheine thyroglobulin.

Ka SHCHZ hormone fepa ho lisele joang?

Hormone SHCHZ tlama ho liprotheine lero la mali, 'me e le ba joalo ba tlisoa lisele le litho tsa ka hare. Ho na le tse tharo mali liprotheine tse khōlō hore li khona ho tlama hormone T3 le T4:

1. TSG - thyroxine-tlama globulin.
2. LSPA - thyroxine-prealbumin.
3. Albumin.

Boemo ba thyroxine le triiodothyronine tšusumetso e SHCHZ secretory mosebetsi le tlamang bokhoni ba serum.

Control T3 le T4 tswakana o etsoang ka li-hormone pituitary TSH (thyroid Stimulating Hormone). Ka lehlakoreng le leng, TSH tswakana e etsoa tlas'a tšusumetso ea hormone tsa hypothalamic TRH (thyrotropin-ho lokolloa hormona).

Free triiodothyronine (fT3)

Pourcentage fT3 ke% 0,25 feela ya palo yohle T3 mali. Joalokaha re bone, T3 maling e tlase haholo ho feta T4, empa, ho sa tsotellehe sena, foromo lona mahala feela halofo T4 freeform.

Ho mahala foromo SHCHZ-hormone e etsa hore mosebetsi oa bona oa tlhaho. Triiodothyronine (li-hormone) tse ling tse ngata ba sebetsa ka mafolofolo thyroxine. Ke ka lebaka leo le se nang boemo ba metabolisticheskoe hae kakaretso ba tsebahala ka bohato hormone thyroid.

Thyroxine: mosebetsi

T4 biologically sa kopanele tšebeletsong. Empa haeba ho hlokahala, a ka tlas'a tšusumetso ea selenium-itšetlehileng ka potlakisang tsebetso ea lik'hemik'hale monodeiodinase fetoloa e T3 le mafolo-folo haholo.

mesebetsi Thyroxine hormona 'meleng o etsa e tšoanang bohlokoa joaloka triiodothyronine. E leng T4 ke le boikarabelo ba ho a hlahise vithamine A ka sebete, di hlohleletsago metabolism protheine, ama lipid (mafura) metabolism, o laola boemo ba triglycerides le k'holeseterole e mpe maling, ama sebopeho e loketseng ea lesapo dinama tse nyenyane tse, e leng bohlokoa ka ho khetheha ka bana ba.

Tsela ea ho nehelana ka tshekatsheka ka li-hormone SHCHZ?

Hore o hlahisa thuto ea phahameng ka ho SHCHZ hormone lopolla mali lekana tswa mothapo ka and analysis ena. Sena se ka etsoa ka kamoreng kalafo.

Phuputso e fetile ka tšeptjoang ka ho fetisisa le liphello ha ba susumetsoe ke lintlha ka ntle, khoeli e 'ngoe pele a fana ka mali bakeng sa and analysis ke ho hlokahala hore kgetholla baeti ba fihlelang ho ya ka litokisetso hormonal. Ya e le hantle, e lokela ho lumellana le ngaka ea hao. matsatsi a 3-5 pele ho letsatsi la ho kgothaletswa ho qhelela ka thōko lithethefatsi tse nang le iodine litareng e ka sebopeho.

Hang-hang pele ho mali mohlala mokuli ha baa lokela ho nka hlahlojoa efe kapa efe X-ray. Bosiung ea ho fana mali e sa kgothaletswa bakeng sa mosebetsi phahameng 'meleng le maemong a sithabetsang (dikgaisano lipapali, litlhahlobo le joalo-joalo. D.). Pele ba kena ho ithuta le ho fetisetsana analysis mamello e kgothaletswa ho lula 'me a phomole metsotso 15-30.

makgabane tloaelehile SHCHZ hormone

Re ile ra fumana hore na ke eng karolo ea 'mele e phetha thyroxine le triiodothyronine, ba tsa maiketsetso ka motheo oa oo dikarolo, e leng lintho tse ba na le boikarabelo serum bona e tlamang, kamoo ho ka fumana teko ya li-hormone tsena. Joale sheba boleng bona ho tloaelehile, 'me tlas'a seo mafu li ka' na eketsa kapa fokotseha. Litekanyetso tsa li-hormone tsena li fanoa ka tafole ka tlase:

Eo mafu a eketsa fT3?

Free triiodothyronine ka e ile ea eketseha ka mafu a latelang:

• Hyperthyroidism ke mathomo kapa se mahareng.
• T3 toxicosis ka thōko.
• Thyroiditis.
• Hypothyroidism T4 manganga.
• Choriocarcinoma.
• ho hanyetsa lefu SHCHZ-hormone.
• Theola ea mahloriso ea thyroxine-tlama globulin.
• Foleng sebete lefu.
• Ka hemodialysis.
• Nephrotic lefu.
• Ka mor'a phekolo le a iodine litareng e ntšang mahlaseli a kotsi.

Maemong a mang, ho na le ea fokotseha fT3?

Theola mali fT3 ka 'na la hlaha maemong a latelang:

• Hypothyroidism ke sa mathomo, se mahareng kapa e phahameng.
• Netireoidnaya bolwetse ba matla, ho akarelletsa maemo a kelellong le 'meleng (setorouku, myocardial le sa t. D.).
• Nako e telele ho itima lijo kapa ho ja ka le tshebediso ya tlaase tsa protheine lijo.
• Nakong hlaphoheloa ka mor'a pathologies tebileng 'me tshebetso.
• Ha uncompensated mathomo adrenal insufficiency.
• Ka basali ba nang le ho ikoetlisa kamehla boima.
• Ka ho trimester boraro ea bokhachane (fT3 boemo ba nakong ea bokhachane butle-butle decreases ho tloha trimester pele le qetellong ea boraro e fetoha ho feta phatlalletsoang).
• Moketeng oa lenyalo la lithethefatsi tse latelang: amiodarone, androgens, propranolol, salicylates, iodinated X-ray fapana le likokoana-hloko.

Ho feta moo, liphetoho ka linako tse itseng lia khoneha fT3. Palo e kahodimodimo ho nako ho tloha ka September ho fihlela February, 'me bonyane ka likhoeli tse ea lehlabula.

matšoao a hypothyroidism

Hypothyroidism - e sa lekaneng tswakana SHCHZ-hormone. Tabeng ena, matšoao a latelang a ka hlaha:

• Lethargy, mokhathala 'me ho otsela.
• Ho hlaha ha boima ba 'mele ho feteletseng o ke keng a laola ka ho ikoetlisa le ho ja lijo.
• Kamehla ho tepella maikutlo.
• Ho ka ba le ea fokotseha ka mocheso oa 'mele ho fihlela ho likhato 35,6.
• Ho hlohlona la letlalo, omile lona le ho ruruha.
• Moriri tahlehelo le dandruff, e leng ha e feta esita le ka mor'a ho sebelisa shampoo e medicated.
• Fokotseha ho otla ha pelo (bradycardia).
• Fokotseha khatello ea mali.
• Tahlehelo ya memori le itšoara joang.
• Kamehla pipitlelano.
• Basali ba ka bakela irregularities matsatsing le ho kgaolela basadi thari.

matšoao a hyperthyroidism

Hyperthyroidism - sena feteletseng tswakana SHCHZ-hormone. Tabeng ena, ho na le matšoao a latelang:

• Eketseha takatso ea lijo 'me kahoo ho lahleheloa ke boima ba' mele.
• Kakaretso bofokoli, khahlanong le eo a ka ba le ka koloi halima.
• Flabbiness le letlalo omile.
• palpitations pelo le khatello e phahameng ea mali.
• Eketseha ka mocheso oa 'mele ho fihlela ho likhato 37,5.
• mafu matsatsing ea basali le ho kgaolela basadi thari.
• Maemong a matla, e le ha ho tshwailwe keketseho e SHCHZ le exophthalmia.

Thibelo ea SHCHZ lefu

The thyroid tsoelesa e le li-hormone tsa lona phetha mosebetsi o itseng oa bohlokoa bakeng sa 'mele, e le hore u lokela ho beha leihlo le boemo ba' mele. Sena se etsoa ka hlahlojoa selemo le selemo. Haeba ho hlokahala, ngaka e tla fana ka tataiso ho oa ultrasound le liteko hormona SHCHZ.

Ho thibela SHCHZ le khaello hormona mafu ea 'mele lokela ho kenyeletsa ka dijo tsa hao lijo tse phahameng ka a iodine litareng e. Tsena li akarelletsa hoo e ka bang tsohle lijo tse tsoang leoatleng (tuna, flounder, litlhapi tsa salmon, makhala, leoatle), tholoana (persimmons, libanana, dilamunu), meroho (eiee, konofolo, sorrel, eggplant). Ka ho latela melao e tataisang e bonolo, o ka ka ho sa feleng boloka bophelo bo botle ba ho thyroid tsoelesa e le bohle ba phelang.