Salmonella tifimurium - pathogen, phumano, kalafo

libaktheria Salmonella tifimurium tsebahalang ka moriana ka Salmonella enterica serovar typhimurium. Ke a mob mobile-mpe, molamu e bōpehileng joaloka libaktheria le flagella (pherese dibopeho moriri-joaloka), eo ka yona phelang tsamaea.

E mong ea bitsoang libaktheria - sesosa se ka sehloohong sa lijo chefo (salmonellosis) ho batho. E le tšoaetso e hangata ka ho fetisisa nama ea kolobe, nama likhoho, mahe. Pets ka boela fetisetsa eona.

Tsela ea ho Salmonella ba classified?

Ho joalo, re na le thahasello ka ho tifimurium Salmonella - causative moemeli ea lefu le joalo kotsi joaloka salmonella. Mofuta oa salmonella enterica e entsoe ka 6 subspecies:

• enterica;
• salamae;
• arizonae;
• diarizonae;
• houtenae;
• indica.

Enterica subspecies enterica akarelletsa ho salmonella latelang serogroups:

• A (paratyphi A).
• B (Derby, typhimurium, agona, heidelberg).
• C (cholerae suis, Newport, muenchen, virchowinfantis).
• D (Dublin, enteritidis, rostock, sendai, typhi).
• E (anatum).

Tifimurium Salmonella (S. typhimurium)

View enterica e nkoa e le pathogenic ho batho le liphoofolo esita le linonyana, empa bohlokoa ka ho fetisisa ke tse seng kae feela ba bona ba ho batho. Le maemong a mangata ba salmonellosis e ileng ea S. typhimurium.

mefuta e mengata ea Salmonella manganga ho lithibela-mafu kajeno, 'me kahoo ba aba lefatšeng ka bophara. Ho joalo, nosocomial salmonellosis - le bothata bo tebileng ka nako eo. Ka 80% ea linyeoe le moemeli causative tsa nosocomial (nosocomial) salmonellosis - ke S. typhimurium.

lintlha pathogenicity

Le kotsi bakeng sa sesosa itse tsa pathogenicity lefu latelang lintlha:

• Flagella fana mokhatlo oa e potlakileng ea kokoana-hloko ena.
• Komiki ea baktheria e sirelelitsoe phagocytes. Le ka lebaka la ho ikhalala ba phagocytosis ntseng li hōla moruong sepsis.

• hlaseloa kenella ka hare tšobotsi etsa hore bothata ntle ho dinama tse nyenyane tse tebileng-ho bua leshano.
• Ka lebaka la ho mamarello molemo (ikamahanya), ho fana ka fibrils, pectins, LP-saccharide rarahaneng, le baktheria e bolokoa ka 'mele.
• Exotoxins (lihlahisoa tsa mosebetsi lona) ho theha letšollo le dehydration morago ga moo, ka potlako vascular e lumellang metsi ho kena.
• Endotoxin ema khahlanong le phagocytosis kotsi. Ho lipopolysaccharide rarahaneng hore bopa botahoa. Platelet aggregation ka methapong tse nyenyane ho lebisa ho ruruha, ho DIC. A secretion ea Na le CL fokotsa mesifa le boreleli 'me e ile ea eketseha mala motility.

Kamoo libaktheria manganga?

Salmonella tifimurium na ho hanyetsa lintlha tse sa tšoaneng tsa tikoloho:

1. likhoeli tse tharo ba li boloketsoe ka mocheso kamoreng amanang beha dintho.
2. Lilemo tse 'nè bolokoa masi omileng ea liphoofolo.
3. likhoeli tse hlano - ka metsing, halofo ea selemo - ka lihlahisoa tsa lebese le nama, ka eggshells - ho fihlela ho ka khoeli.
4. Lefu le hlaha feela ka 100 ° C. Lihlahisoa nama ea ho hanyetsa phahameng ho eketseha mocheso (a ponto ea nama lokela ho phehiloeng ka lihora tse peli, empa ka nako eo ho ke sireletsehileng). Ka thuso ea salting le ho tsuba ha bolaea salmonella.
5. pathogen Sena se ka mamella ka mocheso fokotseha ho -80 ° C.
6. Ho manganga ho UV leseli.
7. sebolaya ditwatsi e hlokahalang ho mamella metsotso e 20 ho ea ho bolaea baktheria.

Ropoha ea salmonellosis incidence hlokomela ea lehlabula, 'me hangata fumanoa ka bana ba banyenyane ba ka lebaka la ho se phethahale ha ba tsamaiso bona sa' mele.

Malwetse a tšoaetsanoang ka ka ho alimentary hape ikopanya le ho ikopanya le-ea lapeng. Ka tsela eo, ke habohlokoa ho sebelisa mahe ho lefa a lebisa tlhokomelo ho mofuta oa protheine le yolk. Ha turbidity, hemorrhage, monko bolileng, lehe e le monyetla tshwaetso. E lokela ho lahloa, lijana tšela chloride matsoho ha ba ntse ba sebetsana le. Sesepa maemong ana ha e thusa.

Mariha le halima, ho shoa ha phahameng le phetiso ea ho ikopanya le-ba ntlo ea mochine oa ho hanyetsa lithibela-mafu li etsahala ka mabaka a le ka lebaka la 'nete ea hore le polokeho ya dijo e gare wa.

nako poloko

Nako poloko nka ho tloha lihora tse tšeletseng ho tse robeli ka letsatsi, empa hangata matšoao a pele hlaha ka hare ho letsatsi la pele kapa tse peli ka mor'a ja sehlahisoa silafetseng.

Ke tlōlo ea metabolism metsi le letsoai e loketseng ho letshollo, setuloana fetoha metsi, frothy, smelly, le meroho, re hopotsang ea "Marsh seretse" le maqhubu a ka makhetlo ho fihlela ho tse leshome ka letsatsi, ka beke kapa ho feta.

Lefu lena le qala acutely, e tšoauoa ka bofokoli, lethargy, bohloko le maikutlo a ka mpeng (epigastric le umbilicus). Mpa e bohloko ka palpation, utlwahala kirietsa le ho ruruha bonahala.

Salmonella tifimurium - laboratori go tlhathoba

Ho fumanoe angoa ke entsprechen latelang:

• eketseha erythrocyte sekhahla sedimentation;
• leukocytes le battlefield ho le letšehali;

Pathogen lemoha tloha maro a likokoana-hloko (mantle, mali, moroto, lekala amehang) le lihlahisoa belaella bacteriological mokhoa. Phello ea ho qetela le joalo, e le busa, e hlophisitsoeng ke letsatsi la bohlano.

Holim 'a tshwaetso ka Salmonella tifimurium, matšoao a latelang:

• feberu;
• chills;
• letšollo le matla;
• ho hlatsa.

kalafo

lefu lena e ka ba e bolaeang ka boseeng, batho ba hōlileng, 'me ka ho bakuli ba sireletsehile maloetseng ana fokotswa. 'Me sena se kotsi Salmonella tifimurium.

Phekolo ke hore o ile a sebelisa lithibela-mafu le ho rehydration. Hape ho laela antispasmodics, litokisetso potlakisang tsebetso ea lik'hemik'hale, sorbents, antidiarrheals. "Lethathamo la Tse №4» bontša lijo.

Phekolo lokela ho ho tshwarwa tlas'a tlhokomelo tieo bongaka, 'me mehato resuscitative sebelisoa maemong a boima. Ea sorbents bakeng sa detoxification ea 'mele e ke ke bohlale ho sebelisa lithethefatsi tse latelang:

• "Enterosgel";
• "Liferana";
• butswe k'habone;
• "Smecta";
• "Enterodeza".

Le khafetsa phehellang ho hlatsa hoa tlamang ho letsetsa ambulense e le hore ho thibela dehydration. Mokuli hangata laetsoeng "Regidron". Eketseha mocheso decreases antipyretics.

Active khahlanong le salmonella salmonella enterica lithibela-mafu

Antibacterial mahlahana a sebetsang a khahlanong le salmonella salmonella enterica, etsa "furazolidone" "Ciprofloxacin", "Rifaximin", "nifuroxazide". Empa ba ile ba ka feela ho laela ngaka, thonaka ka litekanyetso li behoa batho ka bomong le nahane ka boemo ba mokuli, le tšoaetso ea salmonella tifimurium.