Melanoma Phekolo Iseraeleng

Melanoma ke mofuta kotsi haholo oa kankere ea letlalo. mofuta ona wa Ho thehoa ho tswa lisele pigment a letlalo 'me ka ba le kae kapa kae ka letlalo. Baahi e motona ho hlahala le e atisa ho fumanehileng kutu (sefubeng 'me ka morao), halofo e motšehali - ka lipheletsong e ka tlaase.

Hlahala letotong liseleng melanositler hlahisa melanin le teng letlalong, mahlo, likhetla, mucosa molomo, ho Nail sekoti. Tlas'a tšusumetso ea ba bang lintlha melanocytes ka potlako arola le ho hlahisa dae sootho melanin, e le hore kankere Hangata sootho ka 'mala.

A mmala tšoanang le na le matheba a pigmented ka 'mele, papillomavirus ngata, birthmarks, hape e nang le lesihla la melanocytes. Tsena sebopeho le na le matla a ho regenerate ka melanoma ka traumatization khafetsa, combing, ho ts'ebetsong sa potoloho ea lipolanete, ho tlosa bona ka litšekamelo ikhethang ke ligation, cauterization, joalo-joalo

Motho ofe kapa ofe ea hona joale ka 'mele oa 5 ho ea ho 20 diso pigmented (moles) le 7 ka 100 000 selemo le selemo lefatše le mutating lihlopha tsena ka melanoma. Empa thuto melanoma lefifi sootho ka 'na e boetse e hloekisa letlalo.

Nka Lintho ka Botebo letšoao la melanoma tsa letlalo ke ho hloka matheba moriri pigmentation. Mutated ka matheba a melanoma e tla ka potlako hōla 'me fetola' mala ho moriti bo bofubelu pinkish, greyish kapa tse tšoeu. Matšoao a sethaleng e tsoetseng pele ea letotong lefu li carding, tsoa mali ka bosaling, bohloko tsoalo le thuto ka planar e haufi le e le setsi sa matheba a sa tsoa thehoa pigment.

Melanoma metastasizing ho makala tse ling tsa methapo ho - masapo, boko, matšoafo - le aggressiveness ea ho hōla lona e fapaneng.

Tabeng ea lefu belaela ka kalafo ea melanoma Iseraele e qala ka ho hlahloba ka kankere (bophara, tlhaku, mmala, boteng ba ulceration) 'me ba bang ba letlalo, lisele tsa mmele nodes palpable, mamello phuputso e tshwarwa ka matsatsi ao ba bonoa' me matšoao a belaella matheba.

E le hore ho fumana hore na hantle tepelletse maikutlong sebelisoa letlalo biopsy - nka sampole ea epithelium tlas'a thethebatso ea moo ea dikarolo tsa lona holim'a, lateloa ke ho ithuta nyenyane, liteko boitshireletso bakeng sa ho ba teng ha lisele tsa kankere.

Ho batla metastases hlahala 'meleng li sebelisoa sefubeng X-ray, CT, MRI le PET litlhahlobo tsa lesapo ntho mahlaseli masapo.

Le ea moo batla melanoma hangata kgothaletswa ho felisoa ha thuto ea leifo, likarolo tse haufi kamoo ho bonahalang kateng bophelo bo botle tsa letlalo 'me a lemoha metastases vsluchae ha e lumella diriswa bona. Le ata bohlokoa tsa letlalo tlosa ngaka e ka etsa ka letlalo thophothetsa. Mabifi malignancy le potlakisa ho ata ha diso metastatic le maro le mali a bakela kalafo e kopanetsoeng ea melanoma Iseraele.

Healing tsa kalafo lik'hemik'hale e etsoa ka mekhahlelo e morao ea kankere e ntshetswa pele ka limfauzly. Himpreparatov tshelwa ka ente ka leoto, ho ameha kankere hlahala localizing litla bona ka kabelo ea anngoeng ke likoluoa tsa letlalo.

Tabeng ea melanoma metastatic bokong, tsamaiso ya marapo le litho tsa ka hare tse ling tse sebelisa radiotherapy. Ho timetsa kankere 'mele X-ray, ha ho fokotsa boholo ba melanoma e.

Tabeng ea ha namela libakeng tse metastatic sebedisa e ncha kalafo ea melanoma Iseraele - phekolo likokoana-hloko. Ho akarelletsa ho sebelisoa ha meriana tse tšoanang ho lihlahisoa tsa tlhaho (lihaha-'mele, ea tse ling) ya hlahiswa ka hare tsa 'mele ho loantša tšoaetso ea. Lekaneng tlhahiso ea bona "babolai melanoma" etsa tlhahiso eketsehileng liprotheine ka vitro le kenyeletso tsa bona ka boitshireletso ba mmele.

Ho khetholla 'me ba tšoare melanoma Iseraele National Institute melanoma e ile ea hahoa - ea lefatše ho ea kholo ka ho fetisisa ea tleleniki le ho etsa lipatlisiso litsi tse tsoelang pele mekhoa ea phekolo e bakeng sa kankere tlhamosea, ho akarelletsa le buka e ikhethang sehlahiswa Ipilimumab - matla ka ho fetisisa stimulant tlhahiso ea T-lisele tse nang le boikarabelo bakeng sa maloetseng-ba khahlanong le kankere.