"Losek CI": litaelo ho sebelisoa. "Losek CI": kalafo, recensioni, matšoao, contraindications

Na u se u tseba hore, ho tloha sona se etsang hore lithethefatsi ena e le "Losek CI"? Litaelo tsa tšebeliso, hammoho le matšoao tsa lithethefatsi li tla hlalosoa ka sehlooho sena. Ho phaella moo, re tla u bolella kamoo ho fana, o ile a re ho bolela, ha a ne a analogues efe kapa efe le ho contraindications, seo lehlakoreng litla etsahala ka mor'a tsamaiso, le ho feta.

Sebopeho, ambalaji le mofuta o mong oa lithethefatsi e

ke pheko "Losek CI" ke efe? Litaelo bakeng sa ho sebelisoa re tsebisa hore lithethefatsi ena ke e fumaneha feela foromo Letlapa. The a sebetsang a elements moriana o sebetsang sebakeng sa hae omeprazole (10, 40 kapa 20 mg,). Hape matlapa kenyeletsa le ba thusang metsoako: glyceryl monostearate, MCC, hydroxypropylmethylcellulose, hydroxypropylcellulose, magnesium stearate, tsoekere, acid e methacrylic, talc, parafini, triethyl citrate, nhua polyethylene glycol, thaethaniamo dioxide, polysorbate, oxide e tšepe, crosslinked polyvinylpyrrolidone le sodium stearyl fumarate .

Theko moriana o ka 'na ea libotlolong li 14, ya 7 kapa ya 28 matlapa (10, 40 kapa 20 mg,) li ne li kenngoa ka lebokoseng lebokoso.

pharmacodynamics

Joang lithethefatsi "Losek CI"? Litaelo tsa re tšebeliso eo a sebetsang a lithethefatsi ke sesitisa tsa H + -K + -ATPase. Ho feta moo, ho amana le mahlahana a khahlanong le seso. moemeli lona a sebetsang a ke fokolang ho lefisa. Ho e concentrated ka tikoloho acid e ea lisele parietal tsa mucosa gastric, activating le inhibiting proton pompo.

Phello ea omeprazole ka tshebetso ile a hlalosa e lethal dose-itšetlehileng ka eona. A nang le bokhoni moriana o ba fana haholo e atlehang thibelo ea basal le susumelletseha acid e secretion kobosana tsa Ntlha e stimulatory.

Phello ea secretion ea lero gastric

Ka letsatsi molomo moriana o "Losek CI", theko ea eona e tla tšohloa ho se hokae ho feta, e fana ka atlehang le ka potlako thibelo ya bosiu le motšehare secretion ea acid e hydrochloric. Moholo ka ho fetisisa e le hantle phekolo e hlokomela matsatsing a matsatsi a 4 ea phekolo. Batho ba nang le seso 12 duodenal seso 20 mg, ea moriana o baka phokotso tsitsitseng ka lihora tse 24. gastric acidity ea seng ka tlase ho 80%. Ho lokela ho hlokomeloe hore lethal dose ena ya moriana o le khona ho boloka mahareng ka intragastric acidity boemo ba ph> 3. e le hantle ena e ntse e le teng bakeng sa ho lihora tse 17.

Le tsusumetso e mpe ka Helicobacter pylori

Kamoo ka katleho nka bohato khahlanong le eo a re libaktheria moriana "Losek CI"? The Melawana hapa ho moriana, o re omeprazole na le phahameng bactericidal phello Helicobacter pylori. Fele tsa libaktheria nakong kopo ho bolela hammoho le lithethefatsi-ba khahlanong le baktheria e tsamaea le ho felisoa ka toka ka potlako le matšoao 'ohle, hammoho le ka tsela e itseng e phahameng ea ho folisa ba mucosa ba anngoeng le pampitšaneng ena tshilong ya dijo. Ho phaella moo, kalafo ena e khothalletsa nako e telele ho leballa motho ea lefu ulcerative, eo haholo ho fokotsa monyetla oa mali iphetang.

thepa tse ling tsa moriana

thepa seo ba bang ba le ho lokisetsa tse kang "Losek CI"? litsebi Guest stipulate hore bakuli ba kamehla 'me ka nako e telele, noa meriana hore fokotsa secretion ea litsoelesa pampitšaneng ena tshilong ya dijo, hangata hlokomela cysts glandular ka mpeng. E le busa, ba ile ba ba nang kotsi le nyamela ka lithahasello tsa bona.

Theola ea secretion hydrochloric acid e ka mpeng ho khothalletsa batho ho tloaelehile microflora mala. Leha ho le joalo, sena se ka 'etsa hore ba le keketseho e fokolang ka kotsi ea ho tšoaetsoa mafu tse tsoelang pele.

Ho batho ba baholo le bana, nako e telele ho tsoela pele ha matlotlo, ho eketseha ha palo ea lisele tse enterochromaffin hlokomela.

Nakong ea kalafo le mahloriso omeprazole tsa gastrin maling haholo eketseha.

Pharmacokinetics

E ananelang ka meriana maling "Losek CI"? Litaelo bakeng sa ho sebelisoa tiisa hore absorption ea omeprazole le hlaha ka intestine nyenyane (ka hare ho lihora tse 4-6). Lijo ka bioavailability tsa ntho e sa ameha. Ka mor'a tsamaiso molomo e ka bang 60%.

moriana ka ho feletseng metabolized ka sebete. The halofo bophelo bo ka 30-80 metsotso. Hoo e ka bang 80% ea lithethefatsi a sebetsang a e excreted ka metabolites ke liphio, 'me karolo e setseng hammoho le mantle.

ya litatoli na

Tablets "Losek CI" e hlophisitsweng bakeng sa bopengwi latelang:

• mala seso;
• reflux esophagitis;
• seso 12 duodenal seso;
• khoholeho ea mobu ya intestine a bakiloeng ke NSAIDs;
• fele tsa Helicobacter pylori;
• dyspepsia, e leng e tse amanang le acidity phahameng;
• gastroesophageal reflux lefu (bontshang matshwao);
• Zollinger-Ellison lefu.

Contraindications

Ho lokisetsa "Losek CI" a ke ke a ba laela hore hypersensitivity oa mokuli ho omeprazole hammoho le benzimidazoles ka go engwa legatong kapa metsoako e meng hore ke karolo ea moriana.

Ho lokela ho hlokomeloe hore lithethefatsi ena e hlophisitsweng ba hlokolosi ka ho ba teng ha batho ba makgetheng kang sa tahlehelo itlelang feela boima, dysphagia, khafetsa ho hlatsa le ho hlatsa mali. Ho feta moo, gastric seso (kapa lefu belaela) lokela ho qhelela ka thōko ho ba teng ha hlahala bolaeang. Sena ke ka ntlha ya go ha e le hantle hore phekolo le omeprazole ka habonolo pata le matšoao 'me a lieha ho fumanoe nepahetse.

Tsela ea ho nka moriana "Losek CI" (20 mg,)?

Tsa chelete e lokela feela ho ho nkoa ka ka molomo hoseng. lithethefatsi lokela ho metsoa kaofela ka metsi. Lithethefatsi lokela ho silakanya kapa hlafuna.

matlapa a lumelloa ho qhala ka mokelikeli hanyenyane acid e kapa metsi (mohlala, ka dijusi tholoana). Leha ho le joalo, tharollo sephetho le lokela ho chesa ka hare ho hora.

Ha esophageal reflux, gastric le duodenal seso le 12-ho lokisetsa e hlophisitsweng 20 mg, hang ka letsatsi. Ha reflux esophagitis lethal dose ea eketseha habeli.

The nako kalafo ya seso ka libeke tse 2-4 ka reflux esophagitis - libeke tse 4, 'me gastroesophageal reflux - 4-8 libeke tse. Ho thibela relapses tsa liso tsa ka maleng le oesophagitis reflux ka ajwa fumana lithethefatsi lethal dose ka la 10 mg, ka nako e telele.

litla-morao

Medicine "Losek CI" analogs lithethefatsi e ka etsa hore liphello tse. The atileng ka ho fetisisa ba maemo a latelang pathological: hlooho e opang, flatulence, mahlaba ka mpeng, pipitlelano, letšollo, ho nyekoa ke pelo le ho hlatsa.

Bakeng sa litla infrequent lehlakoreng kenyeletsa dermatitis, hives, ho tsekela, ho hlohlona, paresthesia, lekhopho, malaise, ho otsela, e se e eketsehile mosebetsi oa enzyme sebete, 'me lefu la ho hlobaela.

Ho ena le hoo tloaelehang bakuli fumana omeprazole hlaha liphetoho hypersensitivity (mohlala, anaphylactic makala, feberu, anaphylaxis, angioneurotic edema), le bronchospasm, lefu la sebete, bofokoli mesifa, e amanang le sebete ho hloleha, leukopenia, magazine, arthralgia, ho tepella maikutlo, myalgia, pancytopenia, thrombocytopenia, pherekano, agranulocytosis, molomo o omileng, hyponatremia, gastrointestinal candidiasis, mabifi, photosensitivity, pherekano le ho thothofatsang pono, lipono, ho fufuleloa, tatso ea khathatsoa, Periph -geometric edema, stomatitis, interstitial nephritis, alopecia, gynecomastia, etymology multiforme, nyenyane colitis, Stevens-Johnson syndrome, le nang le chefo e epidermal necrolysis.

seoelo haholo o ile a re hypocalcemia, hypomagnesemia, hypokalemia le hypomagnesemia.

Medicine "Losek CI": theko le analogues

Bapisoa le lithethefatsi tse tšoanang, theko ea chelete e haholo phahameng. Ho joalo, bakeng sa matlapa a 14 o tla lokela ho lefa ka bang 250 Russia li-ruble. Ho nahana ka poleloana e reng tsamaiso e telele ea moriana o (libeke tse 2 ho ea ho ea 8), kalafo e theko e phahameng haholo bakeng sa bona.

The ka nkang sebaka sa lithethefatsi "Losek CI"? Analogs oa sesebelisoa sa na le bokgoni tšoanang. Leha ho le joalo, pele o etsa kopo ba, le be le bonnete ba hore ho buisana le ngaka ea hao.

Ho joalo, nka sebaka sa moriana "Losek CI" ka 'na ba meriana e latelang: "Omeprazole Acre", "Vero omeprazole", "Tsisagast", "Gastrozol", "Helol", "Demeprazol", "Helitsid", "Zhelkizol", "Ultop "" Zerotsid "," Ulkozol "," Zolser "," Ulzol "," Krismel, "" The sopranos, "" Losek "," Romesek "," Omez "," Promez "," Omez D "," Pleom- 20 "," Omez Insta "," Peptikum "," Omezol "," Otsid "," Omekaps "," Ortanol "" Omeprazole "" Omitoks "" Omeprazole Richter, "" Omipiks "" Omeprazole STADA " "Omizak", "Omeprazole Zentiva", "Omefez", "Sandoz Omeprazole", "Omeprus", "Omeprazole-OBL", "Omeprazole-FPO" "Omeprazol-Teva", "Omeprazole-Akos".

Testimonials

Seo bakuli ba se buang ka lithethefatsi "Losek CI"? Maikutlo mabapi le setsing sena ke positive, haholo. Ho ea ka tseo ba kileng ba se itse moriana o, e ka tsela e atlehang haholo tlosa matšoao 'ohle a acidity ea lero gastric. Le phello e bonahala hoo e batlang e hang-hang ka mor'a a e-ja matlapa (dihora 1-2).

Hangata e nkoa e le mokhoa sebediswa bakeng sa lesokolla le boikutlo bo tukang ka mor'a breastbone ena.

Ho sa tsotellehe ho bokgoni tse phahameng tsa moriana, bakuli ba ho fetisisa ba tletleba ka hore ka mor'a ho felisoa ha kenoa boemong bo sa thabiseng ea hae ba khutla. Tabeng ena, lingaka li khothalletsa ho khanna e akaretsang kalafo le meriana sebelisoa bonyane libeke tse 'nè.