Lithethefatsi "Itraconazole": setatemente se

Itraconazole (Orungal) e fumaneha ka foromo komiki bakeng sa tsamaiso molomo. Lithethefatsi, ho ba triazole sehlahisoa lipontsuoa mosebetsi ho tšoaetsoa mafu halefisoa ke dermatophytes, tomoso, 'me tomoso-joaloka li-fungus.

The mochine ea nkang khato ea moriana o itraconazole-ratiopharm thehiloeng matla a ho qhala ka tswakana tsa karolo ea bohlokoa ea ho lera seleng ea ea fungus - ergosterol.

moriana o ile a bontša ho dermatomycosis, onychomycosis, halefisoa ke li-fungus, tomoso, 'me dermatophytes, fungal keratitis, systemic mycosis, aspergillosis le candidiasis. pukwanana Itraconazole khothalletsa ho sporotrichosis, histoplasmosis, blastomycosis, paracoccidioidomycosis, candidiasis le diso mucosal kapa letlalo (ho akarelletsa le candidiasis vulvovaginal). Ho bonahala le tsona visceral candidiasis (tebileng), pityriasis versicolor. Ha cryptococcosis (cryptococcal meningitis ka ho khetheha) ka bakuli ba immunodeficiency le bakuli bohle ba nang le cryptococcosis ya bohareng tsamaiso e khopo moriana tšohile "Itraconazole" taeo e dumella ho abela tabeng ea moo pele-line phekolo ha e atlehang kapa ha ho hlokehang.

Ho bolela contraindicated ka hypersensitivity.

Kopo ea ho jara entsoeng ka ka dikgothaletso le tlas'a tlhokomelo ea kamehla ea bongaka. Mabapi le bokhoni ba itraconazole e phunyeletse ka kanyeso lebese nakong phekolo e khaotsa.

Ho sebelisoa ha lithethefatsi ho ka linako tse ling etsa hore bohloko mpeng, ho nyekoa ke pelo, mafu a ho ja, letšollo, ho hlatsa, pipitlelano, neuropathy pheriferale, molikoalikoane, ho eketseha reversible ka potlakisang tsebetso ea lik'hemik'hale sebete, lefu la sebete. Rare ke liponahatso tse kang makala anaphylactic, bolaeang exudative etymology, lekhopho, photosensitivity, angioedema.

Itraconazole. Litaelo tsa tšebeliso

moriana o kgothaletswa ho fumana ka hare hang-hang ka mor'a lijo. Engole le meriana eohle. The litekanyetso li behoa karolelano ea lithethefatsi "Itraconazole" pukwanana khothalletsa ka: 200 mg, hanngoe kapa habeli ka letsatsi.

Bakuli ba lilemong tsa ho etsa bana ba nka lithethefatsi ena lokela ho sebelisa mekhoa e lekaneng ea pelehi ho pholletsa le nako ea phekolo, ho fihlela ponahalo ea nako matsatsing pele ka mor'a qetellong ea phekolo.

Sa kgothaletswa tšebeliso pataganeng tsa itraconazole le lithethefatsi metabolized ke potlakisang tsebetso ea lik'hemik'hale CYP 3A4, e leng e ka lelefatsa (atolosa) le QT karohano. Tsena li akarelletsa, ka ho khetheha, e kenyeletsa astemizole, terfenadine, quinidine, Dofetilide, pimozide, sertindole, Levo le ba bang.

Contraindicated bakeng sa ho sebelisoa ka itraconazole cleavable CYP 3A4-potlakisang tsebetso ea lik'hemik'hale inhibitors reductase tsa HMG-CoA. Tsena li akarelletsa lovastatin, simvastatin.

Sa kgothaletswa bakeng sa ho sebedisana tsamaiso ea itraconazole ka litokisetso tsa alkaloids ergot. Tsena li akarelletsa Ergometrine, ergotamine, dihydroergotamine, metilergometrina.

Tshebediso ya itraconazole lokela ho lumellana le ngaka ea hao. Pele ho nako qetello kapa kopo tsoeng ka fokotsa ho atleha ho phekola le ho se hlahisa liphello tse batlang ea phekolo e.

Ka ho phekola tšoaetso ea fungal ke E le hore le bohloeki botho.

Ka nako e telele ponahatso ea litla-morao lokela rerisane ngaka. Maemong a joalo, kalafo, hangata e hloka ho lokisoa kapa lipotoloho Phetolo sebelisoa litokisetso.

Pele o sebedisa lithethefatsi o lokela ho ka hloko hlahloba litaelo le ho fumana boitsebiso bo qaqileng a buisane le ngaka. Re lokela ho hlokomoloha ka dikgothaletso tsa setsebi sa. Khomarela maemo kalafo tla fihlela sephetho atlehang.