Khoholeho ea mobu ea mala: etiology le pathogenesis

Khoholeho ea mobu ea mala - lefu le ka toka tloaelehileng, e tšoauoa ka sebopeho sa erosions holim'a le lera mucous la mpeng. likoli tsena hlaha hobane necrosis ka ntle feela. Pholiso bona connective lebali e sa thehoa. Khoholeho ea mobu la mala le - ke tlas'a maemo a nosological nako e kopanya iphetang foleng dithulaganyo tse senyang ka mucosa gastric. Ka linako tse ling o bontša ka boeona e le letšoao la gastritis. Ka hona, le ka har'a lingoliloeng tsa ba atisa ho lefu lena o bitsoa erosive gastritis.

Lisosa tsa sehlooho tsa lefu lena le ke ho feteletseng lintlha tsa tikoloho tse kamehla a sebetsa ho ka 'mele oa motho. khatello ea kelello lintlha tsena (chesa, frostbite, kotsi, makala, polytrauma) bakela ho tlōla mekgwa neurohumoral ba molao oa tsamaiso ea makala a mangata, haholo-holo lijo le mesebetsi secretory ea mala le mala, fokotsa ho hanyetsa ea phelang. Ho na le boetse ho na le predisposition liphatsa tsa lefutso ho lefu lena. The khoholeho ea mobu la mala e ka 'na ea boela a hlaha le ho sebelisa meriana (nitrofurans, corticosteroids, acid e ethacrynic, veroshpiron, tolbutamide), tšebeliso e mpe ea lino tse tahang, hammoho le mafu a ea tsamaiso ea endocrine (lefu la tsoekere, hyperparathyroidism).

Ba bangata ba lumela hore le gastritis erosive hlaha ho tswa ho bohato pathogenic tsa Campylobacter (Helicobacter pylori) ka 'mele oa motho. Facts li bontšitse hore 95% ya batho ba nang le liso tsa ka maleng duodenal le tšoaetso ea hantle mofuta ona Campylobacter, empa bakuli ba liso joalo ikarabella ka% 1-6 feela batho bohle ba nang le tšoaetso ea pathogen ena.

Khoholeho ea mobu ea mala: pathogenesis (lefu letotong)

Tlas'a tšusumetso ea lintlha khatello ea kelello 'meleng ho na le rarahaneng le hara amanang dithulaganyo skeletal, tse tsamaeang le mekgwa neural le humoral ba molao oa tsamaiso ea mesebetsi ea tsamaiso ea tsohle' mele, haholo-holo ke mala le mala. Eketseha secretion hormone adrenal cortex le histamine, eo ntlafatsa secretion ea lero gastric le ho eketseha ha tšebetso ea pepsin le dikahare tsa lona tsa acid e hydrochloric free. Ka nako fokotseha e tiileng e qamathelang ea mucus secretion le eo ho fokotsa sireletsang mucosal mosebetsi. Ho phaella moo, ho na le spasmodic khutsufatso ea mesifa ea ea mala le mala, e ile ea eketseha e lumellang metsi ho kena capillary, dinama tse nyenyane tse trophism tšoenngoa, leng isang hamorao ho liphetoho a hlabang, sebopeho sa erosions le liso tsa mucosa gastric. Ho tla ananela 'me phello ea eona hang-hang lintho tse kotsi tse chefo ho mucosa le. Kahoo, ka pathogenesis ea khoholeho ea mobu gastric ke elements senotlolo sa kganetsano pakeng tsa mucosal mokoallo mosebetsi le bokhoni pshatloa dikahare gastric kapa mala. Fanoeng palo ea methapo ea mali ka ho sebaka seo thehoa tsoa mali seso. Ka lefu lena hlahisa tsitsitseng tshebetso mafu a mala, mala, sebete, manyeme le litho tsa ka hare tse ling tse 'me tsamaiso ea.

hangata (30-90%) ka bacha lefu lena le ho na matšoao itseng. Ka linako tse ling bonahalitseng lesokolla, acid e regurgitation, ka seoelo ho ka ba le bohloko ba ka mpeng. Foleng erosive gastritis bontša le matšoao tloaelehileng ea tleleniki. About 80% ea bakuli ba tletleba ba lesokolla, belching, bohloko le tokelo e ka holimo quadrant, bloating, letšollo le pipitlelano.

Bao e leng lingaka fumanoa erosive gastritis, u lokela ho latela lijo tse ikemiseditse ho fokotsa mosebetsi gastric. Ho finyelle pakane ena u lokela ho ja le letona. Pele ho tsohle, ho ja tsa khoholeho ea mobu gastric akarelletsa ho hanela mahoashe lijo faeba hore ke ruileng selulose (radishes, stringy nama le tse bonesitsoeng ka, matlapi a korong bohobe, joalo-joalo). U ke ke ua ja lijo tse halikiloeng. Ho lokela ho ila lino tse tahang, metsi carbonated, dilamunu, kofi, bohobe sootho, hammoho le a batang le chesa lijo.