"Glibenclamide": litaelo bakeng sa ho sebelisoa, ho lokolloa foromo, photo photo photo photo, analogs

ke pheko "glibenclamide" ke efe? Litaelo tsa tšebeliso, foromo lokolloa, analogues 'me ho bonahala ho tsa tsamaiso ya moriana thathamisitsoe ka tlaase mona.

Sebopeho, ambalaji, mofuta o sa lokolloe mahlahana

Foromo seo o entsoe moriana "glibenclamide"? Tataiso e tlaleha hore sesebelisoa e ya hlahiswa ka mokgwa wa matlapa tse kenngoa ka lik'hontheinara polasetiki (kemiso ea sele) le lebokose entsoe ka lebokoso, ka ho latellana.

Sebopeho sa ea lithethefatsi ka eona e kenyeletsa 5 mg, glibenclamide le metsoako ea thusang tse kang litapole starch, lactose monohydrate, magnesium stearate, sodium croscarmellose, Indigo carmine E 132 Colloidal silicon e dioxide e 25, 'me povidone.

ketso ea lithethefatsi

ke lithethefatsi "glibenclamide" ke efe? Litaelo tsa Sebelisa e bolela hore hona ho bolela hore ba bontša le phello hypoglycemic ka batho ba phetseng hantle le bakuli ba nang le lefu la tsoekere la mofuta II.

Ho atleha ha lithethefatsi ena ka lebaka la ho matla a ho eketsa ka insulin secretion ea lisele pancreatic tsa beta ka lebaka la ho tlhotlheletso bona. Ho ea ka litsebi li, phello ena ea moriana e ntlafatsoa le tlas'a tšusumetso ea tsoekere.

Kinetic likarolo e paakanyong molomo

Ke lintho life tse khethollang ba pharmacokinetic lithethefatsi "glibenclamide"? Litaelo bakeng sa ho sebelisoa tiisa hore ka mor'a dosing molomo matlapa a ntho a sebetsang a ka potlako le hoo e ka bang ka ho feletseng ananelang pampitšaneng tshilong ya dijo.

Tsoa hong lijo ja isang phokotso ya glibenclamide mahloriso ka lero la mali (e bapisoa le e mala letho). The mabapi tsa karolo ena le albumin ho feta 98%.

Mokuli a se sebete glibenclamide e fetoloa ho metabolites latelang: 3-cis-hydroxy-glibenclamide le 4-ranole-hydroxy-glyburide. Ba khumo ho fihlela moo e tšoanang ke liphio le, hammoho le mantle ena.

The · nos le bolela'ng ho felisoa halofo ea bophelo ea lithethefatsi ke dihora tse 2-3.5. Ka batho ba nang le phytoteratology mosebetsi sebete, palo ena e haholo tsa fokotswa.

Bontšang bakeng sa tshebediso ya moriana

Maemong a mang, e le lipilisi mamello "glibenclamide" ka abeloa? Hona ho bolela ho kgothaletsa ho nka bakuli ba le lefu la tsoekere la mofuta II, ha ho na le ke ha ho na monyetla ho buseletsa hyperglycemia thata ja lijo le ho ikoetlisa ho, kapa ho lahleheloa ke boima ba 'mele.

Ho thibeloa tshebediso ya

Na ho na le contraindications efe kapa efe ka lithethefatsi "glibenclamide"? Litaelo tsa Sebelisa e bolela hore setsing sena ha ea lokela ho fanoa ho bakuli ba:

• chesa a pharaletseng;
• Hypersensitivity ho motsoako ba mafolofolo, le diuretic thiazide kapa sulfonamides;
• ketoacidosis;
• lefu la tsoekere coma le re prekomatosnoe;
• ntshetsopeleng ya hypoglycemia;
• ho buuoa le ho sithabela tse ling;
• gastroparesis le obstruction mala;
• bokhachane;
• lefu la tsoekere mofuta pele;
• kanyeso.

Moriana o "glibenclamide": litaelo tsa tšebeliso

Nkoa e le ea lithethefatsi lokela ho tsamaisoa feela ke ngaka ea nang le phihlelo. lithethefatsi ena lokela ho kamehla ho ho kopantswe le seratsoana ka tieo. Feela tabeng ena ho tla ba atlehang. litekanyetso li behoa lona itšetlehile ka sephetho le mamello teko (maling tsoekere, litsupa tswang moroto, joalo-joalo).

Ka hona, ho nka lithethefatsi "glibenclamide"? Therapy seo se bolela hore u qale ka tekanyetso fokolang haholo. Sena ke 'nete haholo-holo oa batho ba nang le tšekamelo ea ho ba hypoglycemia le boima ba' mele ka tlase ho lik'hilograma tse 50.

Ka tloaelo ho, ea lethal dose ya pele ya moriana o ke 0,5-1 Letlapa ka letsatsi. Sena se tšoana le 2.5-5 mg, a sebetsang a motsoako. Ha sebetse hantle bohato lithethefatsi boletsweng nomoro ka butle-butle e ile ea eketseha ho matlapa a mararo ka letsatsi, tsamaisanang le mg, 15 ba mafolofolo motsoako o. Sena se lokela ho etsoa ka dikgao ya matsatsi a 'maloa ho fihlela ho beke e le nngwe, ho fihlela sephetho batlang e fihlellwa.

Tsela ea ho fetisetsa mokuli hore lithethefatsi e mong ka moriana "glibenclamide"? Ho sebelisoa ha meriana tabeng ena lokela ho ho phethahatsoa ka hloko feteletseng. Ntlha ea pele, le mamello e hlophisitsweng matlapa ka mor'a lihora tse 0.5, 'me joale butle-butle eketsa lethal dose ea ho ba atlehang ka ho fetisisa.

bakuli ba hōlileng le ba debilitated kapa bakuli ba khaello ea phepo le ho phytoteratology sebete kapa a liphio mosebetsi le ts'ehetsang kapa litekanyetso li behoa ea pele ea meriana e batlang ho fokotsa monyetla oa ho hōla ha hypoglycemia. Hape etsa qeto ka lethal dose e nepahetseng ea lithethefatsi e lokela ho ba le fokotseha boima ba 'mele kapa ha fetola tsela ea lona e tloaelehileng ea bophelo.

mokhoa A ho amohela hypoglycemic Letlapa

Mokhoa oa ho sebelisa lithethefatsi "glibenclamide"? Litaelo bakeng sa ho sebelisoa (photo photo photo photo ea lithethefatsi e fanoeng sehloohong sena) e bolela hore o ne a nka letlapa lokela ho ho nkoa ka pele lijo le khalase ea metsi e tlhotliloeng le le se nang ho hlafuna.

Ka litekanyetso li behoa ea letsatsi le letsatsi ea matlapa a 2, e kgothaletswa ho arola moriana o ka 2 tekanyetso arotsoe (hoseng le mantsiboea) ka karo-karolelano ea 2: 1.

Ke ea bohlokoa haholo ho sebelisa moriana ona ka nako e tšoanang. Siuoe tsa mokete oa letlapa paakanyong hanetsoeng nkiloeng hammoho latelang.

Ka nako ea phekolo le moemeli ena e itšetlehile ka le lefu lena. Ho pholletsa le tsela ea kalafo e hlokahalang ho phetha go baya leitlho e tsoelang pele ea boemo ba dintho phapanyetsano oa mokuli.

litla-morao

The moriana o "Glibenclamide" analogs tse ho tse thathamisitsoeng ka tlaase mona, li ka etsa hore tsoelo-pele ea liphetoho ho sa batleheng amang ea methapo ea kutlo, endocrine, pheriferale le tshilong ya dijo tsamaiso ea le hematopoietic. Tabeng ena, mokuli a ka bonahatsa matšoao a bohloko a kang ho nyekeloa ke pelo, hypoglycemia ba sa tšoaneng ho tiea, e amanang le sebete ho se sebetse, letšollo, hlooho e opang, cholestasis, bofokoli, ho tsekela le mokhathala.

Ho lokela ho hlokomeloe hore ho ja oa sesebelisoa sa ha kgetholla ponahalo ea liphetoho dermatological le alejiki ka photosensitivity, ho hlohlona, letlalo lekhopho le matšoao a tse ling tse sa thabiseng.

Maemong a Overdose hypoglycemic mahlahana

Seo le matšoao a ho etsahala'ng ha e phahameng tekanyetso ya meriana "glibenclamide"? e re Manual eo e overdose, mokuli a ka hlahisa hypoglycemia, mohlomong a tsamaea le bofokoli, boikutlo ba ho tlala, hlooho e opang, ho tšoenyeha, ho fufuleloa ka tsela e feteletseng, ho tsekela, mesifa tremor, palpitations, ho ruruha ea boko, pono le puo e mafu a le.

Kalafo ya maemo a joalo hloka e potlakileng kenoa tsoekere-digestible lijo. Ka mohlala, lero la litholoana, tsoekere, poone sirapo, monate a chesang tee kapa mahe a linotši.

Maemong a matla ho feta, ho ba le mamello e tsamaisoa ka 50% tsoekere tharollo, "Dextrose" "Glucagon" kapa "Diazoxide". E boetse e hloka taolo e khethehileng ea glycemia, creatinine, urea naetrojene, electrolyte le qeto ea hore na ph.

Sebelisana le ka mekhoa e meng ya kalafi

Ha e kopana le ea lithethefatsi nkoa le lithethefatsi-ba khahlanong le systemic, tetracyclines, fluoroquinolones, chloramphenicol, Mao inhibitors, le Ace, H2-blockers, "clofibrate" beta-blockers, probenecid, bezafibrate, "paracetamol", anabolic steroid, ethionamide, allopurinol, pentoxifylline, cyclophosphamide "reserpine", ka insulin le sulfonamides le khona ho potentiate hypoglycemia.

Melato e sebelisa meriana le phenothiazines, thyroid le glucocorticoid hormone, barbiturates, estrogens, diazoxide, progestins, glucagon, matsoai lithium, Adrenomimeticalkie bolela saluretikami nicotinic acid e le derivatives ka fokolisa phello ea oona hypoglycemic.

formulations joalo ba acidified moroto (ho akarelletsa le chloride ammonium, k'halsiamo chloride, ascorbic acid), ka khona ho ntlafatsa ho ketso ya moriana o nahana ka tsona.

Ho sebelisoa ha "glibenclamide" le "rifamycins" eketsa inactivation le ho fokotsa katleho ya pele.

lintlha tse hlakileng

moemeli Hypoglycemic lokela ho hopola le hlokolosi ho bakuli ba nang le ho se sebetse renal le sebete, hammoho le pathological ea thyroid le litsoelesa adrenal, maemo febrile le bokhoba ba tahi foleng.

Hore le phethe kalafo tloaelehile hloka go baya leitlho ea kamehla ea maemo tsoekere maling a le mamello, hammoho le excretion lona.

Haeba ho noa meriana mokuli develops hypoglycemia, le tsoekere e behiloeng hare-hare (ka joalo haeba motho eo ke elang hloko). Ha ba tsebe letho, tsoekere e laolwa entoe, le glucagon - subcutaneously, intramuscularly kapa a entoe. Ka mor'a hore mokuli a ikutloe tsoha, o tla hang-hang fa lijo, ruileng lik'habohaedreite, e le hore ho qoba ho boipheto tsa hypoglycemia.

Theko le analogues (synonymes) mokgwa

Select analogs ea lithethefatsi ena lokela ho feela ba nang le phihlelo litsebi. Bakeng sa lingaka joaloka lithethefatsi kenyeletsa tse latelang: "Manin", "Manin", "Maniglid", "Betanaz" le "Antibet".

Ho lokela ho hlokomeloe hore ho na bapharmasi, hangata e rekisa synonymes oa sesebelisoa sena. Tshebediso atileng ka ho fetisisa ba, "Glidanil", "Glibeks", "Glibamid", "Gilemal", "Glibomet", "glibenclamide". The litekanyetso li behoa ea chelete tsena e khethiloeng le batho ka bomong.

Ha e le theko ea "glibenclamide" lithethefatsi, ho fapana ka mefuta e fapaneng 280-360 li-ruble.

Reviews of moriana

Hona joale u tseba hore ke lithethefatsi "glibenclamide". Litaelo bakeng sa ho sebelisoa, 'me sebōpeho sa analogues ea mokhoa tse boletsoeng ka holimo.

Seo ba se buang mabapi le basebelisi ena lithethefatsi? E le busa, melaetsa eohle ka eona ba fokotswa ho puisano ea batho ba kapa regimens tse ling ho phekola hore ba kgothaletswa bakeng sa batho ba nang le lefu la tsoekere.

Bareki re hangata ka ho fetisisa "glibenclamide" e sebelisoa ka monotherapy ka. Leha ho na le ba bakuli ba beuweng lithethefatsi hammoho le lithethefatsi tse ling tse hypoglycemic.

Ho ea ka lingaka, ho kgethwa ha moriana ka eona e hloka e mokgwathupelo motho. Tabeng ena, setsebi e lokela ho ba tloaelane le sephetho kaofela ditshekatsheko, 'me lithuto tsa tse ling. Nka "glibenclamide" bakuli ba ka masene bona ke kotsi haholo ho bophelo bo botle le bophelo.