"Flosteron": litaelo bakeng sa ho sebelisoa (liente), recensioni, contraindications

Ho boleloa'ng lithethefatsi "Flosteron"? Litaelo bakeng sa ho sebelisoa (liente), likarabo tse bontšitsoeng tlaase mona. Re boetse re u bolella mabapi le ea mofuta ofe sebopeho ke lithethefatsi tseo o ile a re ka eona, bakuli, hore na o na le litla-morao le contraindications efe kapa efe lokela ho tseba pele ho sebelisa meriana e laela.

Sebopeho sa tsa bongaka sesebelisoa, ambalaji le mokgwa wa

e meriana ho lokolloa foromo "Flosteron" ke efe? Litaelo bakeng sa ho sebelisoa (liente), litsebi li ea sebele bolela hore sesebelisoa sena ka rekoa feela ka mokgwa wa ho fanyeha, e leng e ne a rerile hore ente.

Lintho tse mafolofolo tsa ho lokisetsa ena ke tse latelang: betamethasone diprolene dipropionate le betamethasone diprolene disodium phosphate. Ka rekisa fanyeha bo fihla ka ampoules, tse kenngoa ka ambalaji ea moeli polasetiki.

Litšobotsi diokobatsi ya moriana

ke pheko e le "Flosteron" ke efe? Litaelo bakeng sa ho sebelisoa (liente), le lekodisisa lingaka re ho atleha ha lithethefatsi ena ka lebaka la ho sebopeho lona.

Betamethasone diprolene ke corticosteroids maiketsetso. O na le desensitizing,-ba khahlanong le a hlabang, antishock,-ba khahlanong le alejiki, immunosuppressive le phello-ba khahlanong le nang le chefo e. Hape, moriana o eketsa excitability tsa tsamaiso ea methapo, ho fokotsa palo ea eosinophils le lymphocytes, eketsa palo ea lisele tse khubelu ea mali (ka lebaka la ho ntlafatsoa erythropoietins paakanyong).

Nkoa e le moemeli habonolo a leka ho le receptors cytoplasmic di hlohleletsago RNA tswakana, ya ho theha e rarahaneng, e leng se kenella ka hare ho sele khubu.

mochine oa bohato

Joang lithethefatsi "Flosteron" ente? O akarelletsa'ng ka mafolofolo hoo e ka bang dithulaganyo tsohle tshilong ya dijo ka 'mele.

Lipid metabolism. ba lokisetsa ho ea ho eketsa tswakana ya thyroid-Stimulating Hormone, 'me ea acid tse mafura (e phahameng). Ho redistributes mafura le isang hypercholesterolemia.

Protein metabolism. Moriana o "Flosteron" eo ho hlophisoa e ne e tla a emela ka holimo, ho fokotsa palo ea protheine ka lero la mali e. Kahoo eketsa coefficient tsa albumin le globulin, albumin tswakana eketseha ka a liphio le sebete, empa hape kgothaletsa protheine catabolism ka dinama tse nyenyane tse mesifa.

K'habohaedreite metabolism. Seo batho ba se buang mabapi le litsebi ena lithethefatsi? Ho thoe'ng ka ho mo siea ulasan pelanggan? "Flosteron" - ya moriana o buka e ikhethang eo kgothaletsa ho absorption ea lik'habohaedreite pampitšaneng tshilong ya dijo, eketsa tswakana le mosebetsi oa aminotransferases fosfoenolpiruvatkarboksilazy hore etella pele ho ho kenya tshebetsong ya gluconeogenesis, 'me se eketsa phepelo ea tsoekere e tsoang sebeteng ka maling.

Metsi le metabolism electrolyte. Ho Phekola "Flosteronom" khothalletsa Na + le tshegetsa le go tlotla metsi 'meleng, e di hlohleletsago ea excretion ea K Ho fokotsa absorption ea Ca ²⁺ tloha intestine le, flushes e tsoa ho e bone bone, 'me hape ho eketsa excretion ke liphio.

The thepa ya moriana

Seo thepa ya lithethefatsi "Flosteron"? Litaelo bakeng sa ho sebelisoa (liente), ulasan pelanggan ba tsebisoa hore tšebeliso ea lithethefatsi o na le litla latelang:

• -Ba khahlanong le a hlabang. e le hantle ena e amanang le ea fokotseha ka palo ea lisele tse palo tse hlahisang acid e hyaluronic hammoho le hatelloang tsa mediators a hlabang hore ba lokolloa ke eosinophils.
• Antiallergic. kgahlamelo ya maqhubu a joalo e ntshetswa pele ka lebaka la hatelloang ea secretion le tswakana tsa mediators tsa allergy, hammoho le thibelo ya histamine lokolloa ha basophils le lisele tse palo.
• -Ba khahlanong le nang le chefo e le antishock. e le hantle ena e hlaha ka lebaka la ea ho eketseha ha khatello ea mali, fokotseha vascular e lumellang metsi ho kena 'me Tshebediso ya ha marako a potlakisang tsebetso ea lik'hemik'hale sebete.
• Immunosuppressive. e le hantle ena e bakoang ke thibelo ea ho lokolloa ha ea tse ling ho tloha macrophages le lymphocytes.

Pharmacokinetics mokgwa

Kamoo re lokelang ho tšoara ba lithethefatsi e ananelang ka nako e telele? Seo batho ba se buang mabapi le ditshwaelo tsa see? "Flosteron" - lithethefatsi bakeng sa ente intraarticular. Ka mor'a ho sebelisa e moriana o lebetsoeng le lero la mali mahloriso e ile ea fihla ka mor'a e ka bang halofo ea hora.

Lithethefatsi tlama ho liprotheine habonolo le feta mekoallo ea mali-dinama tse nyenyane tse, ho akarelletsa le placental.

Metabolism le hlaha ka moriana o sebete. Ka tsela eo ha thehoa metabolites haholo-holo a sa kopanele tšebeletsong. Khumo e ka tsela liphio, hammoho le ka e nyenyane hammoho le bile le lebeseng.

Ho bonahala ba moriana

Nka sebelisa lithethefatsi "Flosteron" ka psoriasis, ramatiki le mafu a mang? Lethathamo la matšoao oa sesebelisoa sa tla tšohloa mona ka tlase.

Ka kalafo ea lihlooho tsa puisano tsa:

• bakeng sa tsamaiso intra-articular ka ho ba teng ha synovitis, hammoho le ka mafu a mang rheumatic holofatsang (haeba leha e le efe a ke ke a sebelisoa ka tabanan manonyello le noka) ;
• okolosustavnogo bakeng sa ente intraarticular le rheumatic mafu a hlabang (seronegative spondylitis, ramatiki e ruruhisang, ramatiki ka systemic connective lefu dinama tse nyenyane tse), psoriatic ramatiki tenosynovitis le le diso tsa manonyeletso, ramatiki le bonaletsang posttraumatic ramatiki;
• bakeng sa kalafo ya diso hlabang periarticular lisele (epicondylitis, bursitis, tenosynovitis, plangarnye fasciitis le tendinitis);
• bakeng sa kenyeletswa ka lethopa ea ho phekola mafu a letlalo (ka joalo haeba ha ho na lebaka la mekhoa e meng ea phekolo ea moo): psoriasis, folliculitis sclerosing, alopecia areata, keloids, nummular eczema, granuloma annulare, boriba planus, letlalo sarcoidosis, dermatitis, lefu la tsoekere lipodystrophy le systemic lupus erythematosus discoid.

E le kalafo systemic ya:

• systemic lithethefatsi e le hantle "Flosteron" e sebediswa feela ha itseng alejiki mafu (Quincke edema, alejiki rhinitis, Metsu ea likokoanyana, boemo asthmatic le kulisa ho lithethefatsi).

Lithethefatsi "Flosteron": contraindications ho tshebediso ya

Pele o etsa kopo sehlahiswa tlas'a ho nahanela e lokela ho ba bonnete ba hore bala litaelo khomaretse. Sena ke ka ntlha ya go ha e le hantle hore moriana o le mafolo-folo e na le palo e khōlō ea litla-morao. Nahana ka lethathamo la tsona hona joale:

• osteoporosis;
• peptic seso sa duodenum kapa mpeng, diverticulitis, mala anastomosis;
• glaucoma;
• thrombophlebitis;
• lefu Cushing ya;
• lefuba;
• boemo ba ka mor'a ho buuoa le likotsi tse batlang li tebile;
• lefu la tsoekere;
• idiopathic thrombocytopenic purpura (bakeng sa tsamaiso intramuscular feela);
• hlobaetsang fungal, baktheria le tšoaetso ea bongata ba kokwanahloko (haeba kalafo loketseng ho tse e sa atlehe);
• poso-ente nako (likhoeli tse 2 pele le bakeng sa libeke tse peli);
• ho ba sieo ha matšoao a ho ruruha ka kopanetsoeng;
• periartrikulyarnye tšoaetso, a tšoaetsanoang (kapa ho thoeng maswe) ruruha ka manonyeletso;
• chrezsustavnoy lesapo fracture;
• se tsitse ha e kopanetsoeng ka lebaka la ramatiki;
• fetileng arthroplasty;
• necrosis (aseptic) epiphyses la masapo a eaba ba etsa e kopanetsweng;
• haholo kopanetsoeng deformity le ho timetsoa ha lesapo;
• taolo ho Achilles tendon;
• diabolololo;
• tsoa mali tlhaku pathological;
• eketseha nahanela ho betamethasone diprolene motho, hammoho le leha e le efe mahlahana a tse ling tse karolo.

Ka lebaka la 'nete ea hore lithethefatsi "Flosteron" e na le benzyl joala, ho ka' na ha sebelisoa ka neonates le bana ho fihlela ho lilemo tse tharo.

Mekhoa ea ho Sebelisa le litekanyetso li behoa

Moriana o "Flosteron" psoriasis (ulasan pelanggan ya moriana o tla hlahisa mona ka tlase), hammoho le mafu a mang a sebelisoang parenterally. Ka mantsoe a mang, le moriana o tlas'a ho nahanela ba lumelloa ho sebelisa bakeng sa intra-articular, okolosustavnogo le tsamaiso intradermal. Ho lokela ho hlokomeloe hore maemong a ikhethang e laolwa intramuscularly.

Lethal dose bakeng sa batho ba baholo le bana ba banyenyane ba ikemiselitse le batho ka bomong. molumo itšetlehile ka mofuta wa ho tiea tsa lefu lena le, e le karabelo ea mamello, boholo le sebaka sa kopanetsoeng, 'me joalo-joalo.

Periarticular le intraarticular tsamaiso:

• manonyeletso kgolo (hangata ho noka) - 2.1 di ml;
• manonyeletso kgolo (ka mahetla, lengole, leqaqailaneng) - 1 di ml;
• manonyeletso karolelano (elbows, wrist) - 0.5-1 di ml;
• manonyeletso nyenyane (interphalangeal, metacarpophalangeal, sternoclavicular) - 0.25-0.5 di ml. Hlobaetsang gouty ramatiki hloka ho sebelisa ho tswa di ml 0.5 ho 1 ya sehlahiswa.

Liente ka manonyello a kgolo lokela ho etsoa ka makhetlo a se na ho feta 3-4 ka selemo. A litekanyetso li behoa 'ngoe ea lithethefatsi ha ea lokela ho ba phahameng ho feta 0,2 di ml ka ho ya ka ^cm2.

khukhuneloa Local:

• tendonitis le tenosynovitis - 0.5 di ml;
• bursitis - ka 0.25-1 ml tse (ka mohato hlobaetsang ho 2 di ml);
• fibrositis ka - 0.5-1 di ml.

Lithethefatsi e sebediswa mong le e mong libeke tse 1-2. Haeba hlokahala, paakanyong ka ente e 'ngoe li ne li tsoakane le moriana o thethefatsang kutlo ea moo.

tsamaiso systemic ba kulisoa:

• le 'ngoe litekanyetso li behoa - ho tloha ho 1 ho 2 di ml (feela intramuscularly).

The moriana o e tshelwa tebileng ka mesifa gluteus.

Masea a tloha ka ba lilemo 3 ho ea 5 ea lethal dose ea pele ea 2, mg, 'me lilemo tse 6-12 - 4 mg,.

overdose

Tabeng ea overdose ka bakuli ba latelang matšoao a ka 'na la hlaha: pherekano, ho nyekoa ke pelo, lefu la ho hlobaela, ho hlatsa, ho tepella maikutlo le nyakallo. sebelisoa ka nako e telele ya chelete ka dosages phahame lithethefatsi bakang myopathy, osteoporosis, tshegetsa le go tlotla metsi, lefu Cushing e, e ile ea eketseha khatello ea mali le thibelo ea adrenal cortex tshebetso. Bakeng sa kalafo ho hlokahala hore ho fokotsa tsebeliso ea lithethefatsi, 'me ka nako eo ka ho feletseng felisa e.

Ditlamorao tsa lisebelisoa

Lithethefatsi "Flosteron" ha ea lokela ho sebelisoa nakong ea bokhachane. Sena ke ka ntlha ya go ha e le hantle hore lithethefatsi ena e na le palo e khōlō ea litla-morao. Ba ka 'na etsahala ka lehlakoreng la litsamaiso tsohle le makala.

• tsamaiso e khopo Endocrine: hirsutism, fokotseha ka tsoekere mamello, ntshetsopele thobalano kholofalo baneng le bacha, steroid lefu la tsoekere, 'me joalo-joalo.
• Tshilo ya dijo: erosive esophagitis, oropharyngeal candidiasis, pancreatitis, ho nyekoa ke pelo, fokotseha, jj ..
• Lijana le pelo arrhythmia, hypercoagulation, bradycardia, thrombosis venous, 'me joalo-joalo.
• tsamaiso ea methapo: lipono, hlooho e opang, ferekane kelellong-kelello bo, ho tepella maikutlo, ho tsekela, disorientation, pseudotumor cerebellum, nyakallo, ho tšoenyeha paranoia, joalo-joalo ...
• Hlaphohetsoe likelellong: liphetoho trophic tsa cornea, e le tahlehelo ea tšohanyetso ea pono, subkalsulyarnaya lera, tšoaetso leihlo, diplopia, exophthalmos, 'me joalo-joalo.
• Metabolism: hypernatremia, hypocalcemia, sodium le tshegetsa le go tlotla mokelikeli ka boima ba 'mele ho rua ho.
• tsamaiso e khopo Musculoskeletal: mesifa tendon otlile, khōlo ea kholofalo baneng, osteoporosis, steroid myopathy, proximal mesifa bofokoli, ho lahleheloa ke mesifa boima.
• Letlalo le lera la mucous: felloa ke matla tsa letlalo la, petechiae, thinning ea letlalo la, ecchymosis, steroid maqoqomete, ea liehang ke pholiso maqeba.

ditshebeditsano lithethefatsi

Pele ho sebelisa chelete e hlokahalang ho tseba hore na ho ka khoneha ka nako e tšoanang le meriana e meng ea ho sebelisa lithethefatsi "Flosteron".

• The thibela likepe eketsa mesifa ha sebedisa corticosteroids tse ling.
• The bohlokwa ba tsamaiso ea betamethasone diprolene haholo fokotswa ha e laolwa hammoho phenobarbital, rifampicin, phenytoin le carbamazepine.
• Arolelana lithethefatsi "Flosteron" le ritodrine contraindicated, e le motswako ena ho ka etsa hore edema methapo.
• Ka kopo e sa le masoha le ente antiviral (phele) ho eketsa kotsi ea tshwaetso le ho Tshebediso ya tsa likokoana-hloko.
• ba lokisetsa ho ea ho eketsa toxicity ea asparaginase decreases phello ea somatotropin, 'me hape ho fokotsa metabolism tsa cyclosporin.

"Flosteron" kapa "Diprospan": e molemo?

Ntho mafolofolo chelete bobeli ke e tšoanang, empa ka tsela e tšoanang sebopeho. Empa ho sa tsotellehe sena, litsenyehelo tsa ho ba ea pele e tlase haholo ho feta hore ba bobeli. Sena ke karolo e 'ngoe e loketseng ho moetsi oa moriana. Leha ho le joalo, litsebi tse ling li pheha khang ea hore "Flosteron" meriana e atlehang haholoanyane. Ka nako e tšoanang, re ela hloko hore ho na le ba e ngata haholo ea poeletsotlaleho ntle ka ho moriana o "Diprospan". Bakuli ba bolela hore lithethefatsi ena le lintho tse ngata tlase litla-morao. Ho hoo e batlang e ha e etsa hore kulisa le e batlang e le hantle mameletse. Ka nako e tšoanang ha ba arabela hantle ha ba meriana, "Flosteron", a bua ka katleho ha eona. Leha ho le joalo, e lokela ho ka boleloa hore bohle feela motho mona.

Ke tsela eo, potso ea Phetolo ya ke mokhoa o mong o lokela ho etsa qeto ea feela ka mor'a hore a buisane le ngaka ea hao.

analogues ya chelete

Ho phaella ho ea lithethefatsi le "Diprospan" lithethefatsi "Flosteron" o counterparts tse ling. Tsena li akarelletsa lithethefatsi tse latelang: "Akriderm" "betamethasone diprolene sodium phosphate", "Akriderm Ghent" "betamethasone diprolene valerate," "Betnoveyt", "Tselederm", "Beloderm" "betamethasone diprolene dipropionate," "Beloderm Express", " Tseleston "," Diprospan "," Betazon "," Celestoderm-In, "" betamethasone diprolene "," Betliben "," Kuterid ".