Lithethefatsi "Sporagal": litaelo bakeng sa ho sebelisoa, analogs le ulasan pelanggan

Tsela ea ho nka lithethefatsi "Sporagal"? Litaelo tabeng ea ho sebelisa lithethefatsi le tla tšohloa ka ho eketsehileng. U tla boela u ithute hore na ho na le analogues ya ba lokisetsa ho sena, kamoo ho fana, re ka mo bakuli, ka morero ofe e laolwa, 'me joalo-joalo. D.

Foromo ya, sebopeho, ambalaji antifungal lithethefatsi

Ho lokisetsa "Sporagal" fumaneha ka foromo komiki. Lona a sebetsang a motsoako o ka sehloohong ke itraconazole. Hape le moriana o kenyelletsa ditokiseletso nhua polyethylene glycol 20000, sucrose, le hydroxypropyl acrylate copolymer.

Mabapi le khetla, e entsoe ka edible gelatin, thaethaniamo dioxide le indigotin.

Ka sephutheloana sa e rekiswa moriana "Sporagal"? Litaelo tsa ho sebelisa sesebelisoa sena se aa ageletsweng ka lebokose lebokoso. E boetse e na le ka thata edible gelatin komiki le leputsoa (ka machachetsi), eo na le granules chitja tsa 'mala o mosehla.

Pharmacodynamics moriana o

Joang "Sporagal" Letlapa? Ho ea ka litaelo tseo, ka ea lithethefatsi ke sehlahisoa sa triazole. Ho na le mosebetsi o phahameng khahlanong le li-fungus.

Lithethefatsi thusa liehe tswakana likokoana-hloko tsa ergosterol, ho fana ka le phello antifungal.

Litsebi li bolela hore itraconazole thibela kgolo le ho ikatisa ya palo e khōlō ea mefuta ea li-fungus.

The pharmacokinetics ba moemeli antifungal

Lithethefatsi "Sporagal", eo analogues tla boletsweng eketsehileng, ka potlako kena maling. Boemo phahameng ka ho fetisisa ya itraconazole batho e ketekoa ka mor'a lihora tse 3. bioavailability lona ke 55% (palo e kahodimodimo ho e hlokomela ka capsules sa baeti ba fihlelang ho tshebediso ya mafura le tse phahameng-khalori lijo tse hang-hang latelang).

Itraconazole e abeloa makala a fapaneng le lisele tsa 'mele. dikahare tsa lona ka masapo, ke phenya liphio, sebete, matšoafo, mesifa ya marapo, mala, spleen le makhetlo a 3 phahame ho feta ka mali.

Moriana o metabolized ka sebete le ho lokolla ka plurality tsa derivatives. Leha ho le joalo, feela gidroksiitrakonazol na le bitsoa joang le phello antifungal.

Hoo e ka bang 34% ea lithethefatsi a sebetsang a e lokolloa ka moroto, 'me ka 54% ka intestine le.

Ka batho ba nang le litsebeng sebete mosebetsi le lefu a liphio, 'me ka ho bakuli ba immunosuppression bioavailability ya moriana ka fokotsehile.

ho bonahala capsules

Hobaneng a khethe "Sporagal"? Thupelo ea bolela hore lithethefatsi e ne a rerile hore ho phekola tšoaetso ea fungal, tse neng li halefile ke likokoana-hloko lithethefatsi nahanela:

• vulvovaginal candidiasis;
• mafu a ophthalmological le dermatological se hlahang ho yona fungal (mohlala, fungal keratitis, ringworm, pityriasis versicolor);
• molomo candidiasis ;
• onychomycosis, tse neng li halefile ke dermatophytes kapa tomoso;
• mycoses systemic ho akarelletsa cryptococcosis (batho ba le tsamaiso fokolang boitshireletso nakong tsamaiso ea methapo cryptococcosis moriana o laolwa feela ho ba sieo ha litla kalafo ya mahlahana a tse ling tse antifungal), cryptococcal meningitis, systemic aspergillosis le candidiasis;
• sporotrichosis, paracoccidioidomycosis, blastomycosis, histoplasmosis, 'me tse ling tse sa tloaelehang mycoses systemic.

Contraindications ho tshebediso ya capsules

ke contraindications ho tšebeliso ea sethethefatsi "Sporagal" (matlapa) eng? Thupelo ea bolela hore lithethefatsi ha sebelisoa ka ho:

• Hypersensitivity ho dikarolo mathomo le se mahareng sa moriana
• hammoho le meriana tse kang "Eletriptan" blockers HMG-CoA inhibitors reductase (mohlala, "atorvastatin", "Lovastatin" "simvastatin"), ergot alkaloids, substrates CYP3A4 (ka mohlala, "Cisapride", "bepridil," "pimozide" "Dofetilide", "Astemizole" "quinidine" "mizolastine"), "nisoldipine," "Midazolam", "triazolam".

E lokela ho ile a hlokomela hore ho sebelisa lithethefatsi ena e contraindicated bakeng sa batho ba nang le ho se sebetse ventricular le ha pelo, haholo-holo congestive botho ba hae.

Lithethefatsi "Sporagal": litaelo tsa tšebeliso

Ho ea ka litaelo tseo, ka ea lithethefatsi lokela ho feela ho ho nkoa ka ka molomo. capsules lokela ho chesa hang-hang ka mor'a lijo (e le hore ho etsa bonnete ba molemo absorption), ka kakaretso, ntle ho hlafuna.

The litekanyetso li behoa ea meriana ena e itšetlehile ka mofuta oa lefu jaana:

• Dermatological le ophthalmologic lethopa (mohlala, pityriasis versicolor kapa ringworm) - 200 mg, hang ka letsatsi bakeng sa beke.
• diso Keratinized tsa letlalo (matsoho le maoto a) - 200 mg, ka makhetlo a mabeli ka letsatsi, ka beke.
• Vulvovaginal candidiasis - 200 mg, ka makhetlo a mabeli ka letsatsi, ka matsatsi a mararo.
• Molomo candidiasis - 100 mg, hang ka letsatsi libeke tse peli. Ka bakuli ba AIDS kapa neutropenia, lethal dose e nyolohetse ho 200 mg, hang ka letsatsi.
• Fungal keratitis - 200 mg, hang ka letsatsi bakeng sa ho libeke tse tharo.
• Onychomycosis, tse neng li bakoa ke dermatophytes kapa tomoso, ba tšoaroa ka tsela ya dithuto pheta. phekolo e 'ngoe ho akarelletsa ho ho nka capsules pedi habeli ka letsatsi bakeng sa beke. Bakeng sa kalafo ya diso Nail menoaneng e phethahatsoa dithuto 2 tsa phekolo ena, 'me ka maoto a hae a - 3 dithuto. The khefu pakeng tsa tse peli e lokela ho ba libeke tse 3. phello ea e bontšoa ka mor'a 'nete hore ho phethoa (ka khōlo ea lipoleiti Nail).

Sebakeng seo ba lokisetsa ho "Sporagal" tsa Nail le letlalo o etsoang tsoa bakeng sa ho feta ho tloha maling. Tabeng ena, ho homolog phekola liphello tsa bakuli ba finyelloa libeke feela ka mor'a hore tse tharo ka mor'a phethoa phekolo ea mafu a tsoaetsanang le hoo e ka bang 9 likhoeli ka mor'a ho phekola onychomycosis.

Mekhoa ea ho Sebelisa capsules bakeng diso systemic

Joalokaha eka ke ka diso systemic etsa kopo ee? "Sporagal" kgetha ka dosages tse latelang:

• Candidiasis - 100-200 mg, hang letsatsi le letsatsi bakeng sa dibeke tse 5-30.
• Cryptococcosis ntle meningitis - 200 mg, ka letsatsi bakeng sa likhoeli tse 3-12. Le meningitis habeli lethal dose.
• Aspergillosis - 200 mg, ka letsatsi bakeng sa likhoeli tse 3-5.
• Histoplasmosis - 200 mg, ka makhetlo a mabeli ka letsatsi, ka likhoeli tse robeli.
• Chromomycosis - 100-200 mg, ka ho ya ka letsatsi le letsatsi ka likhoeli tse tšeletseng.
• Sporotrichosis - 100 mg, ka ho ya ka letsatsi le letsatsi ka likhoeli tse tharo.
• Paracoccidioidomycosis - 100 mg, letsatsi le letsatsi bakeng sa likhoeli tse tšeletseng. Bakeng sa bakuli ba AIDS, litekanyetso li behoa ea ka e ile ea eketseha.
• Blastomycosis - 100-200 mg, ka makhetlo a mabeli ka letsatsi, ka likhoeli tse tšeletseng.

Le litla-morao tsa meriana

Na ho na le litla-morao ka bakuli ba fumana "Sporagal" lithethefatsi? profesionalce Reviews tlalehela liphetoho tse latelang:

• neutropenia, thrombocytopenia, leukopenia;
• tsoaetsanang matšoafo pampitšana (ka holimo);
• hypertriglyceridemia, hypokalemia, hypocalcemia;
• hlooho e opang, paresthesia, neuropathy pheriferale, hypoesthesia, ho tsekela;
• serum kula, angioneurotic edema, anaphylactic le anaphylactoid kulisa;
• thothofatsang pono, diplopia, utloa tahlehelo, tinnitus, pono thothofatsang;
• pelo ea hloleha, haholo-holo congestive tlhaku;
• dyspnea, rhinitis, sinusitis, edema methapo;
• ho hlatsa, dyspepsia, liphetoho hepatotoxic, bohloko mpeng, pancreatitis, ho nyekoa ke pelo, dysgeusia, pipitlelano, lefu la sebete, letšollo, bloating, nakoana bophahamo ba transaminases sebete;
• bohloko le manonyello le mesifa;
• lekhopho, photosensitivity, leukocytoclastic vasculitis, alopecia, chefo epidermal necrolysis, pruritus, exfoliative dermatitis, lekhopho, a hlobaetsang le generalized exanthematous pustulosis, etymology multiforme;
• dysmenorrhea, mosese incontinence, erectile ho se sebetse, pollakiuria;
• feberu, edema.

likhothaletso itseng

Seo u lokelang ho se tseba le mamello, pele ho nka lithethefatsi "Sporagal"? Likarabo e ile ea tlaleha hore ntho lona a sebetsang a na le mpe inotropic sebediswa.

Ha a ntse a ho noa meriana ena e ka hlahisa congestive pelo hloleha, le hepatotoxicity matla.

Ha fokotswa acidity lithethefatsi absorbability oa soahlamana.

Batho ba ka nako ho sebelisa antacids lokela ho a lula pakeng tsa bona le mekhoa ea ho lokisetsa a hlalosa karohano ya dihora tse 2.

Lithethefatsi "Sporagal" sa kgothaletswa bakeng sa bakuli ba hōlileng.

Haeba u na le matšoao a pheriferale neuropathy tebisetsang meriana ho hlakola.

Kanyeso le ho ima

Nakong ea bokhachane, meriana e ka tsamaisoa feela mycoses systemic, e leng a le kotsi ho bophelo ba 'mè oa.

Ha e le kanyeso, ka nako ena, "Sporagal" lumelloa, empa feela ka tlas'a bontšang tieo.

Lithethefatsi "Sporagal": analogs le theko

The lisebelisoa tse latelang ke analogues ho fetisisa e tsejoang ea moriana tlas'a nahanela, "Itrungar", "Sporaksol", "Orungal", "Eszol" le "Funit".

Ke bokae sethethefatsi "Sporagal"? Theko ea meriana ena fapana pakeng 1100-1200 li-ruble.

Reviews of ho lokisetsa

Ho ea ka poeletsotlaleho ea ba ileng ba o ile a nka lithethefatsi, ho ka 'na ho hlokomela hore ho ke ke e atlehang haholo bontša ka boeona e ka mefuta e fapaneng ya ho tsoaetsoa mafu a fungal. ka thōko ho tloha melaetsa e mpe ba elang hore re sesebelisoa sena se na le theko e phahameng. Leha ho le joalo, litsebi li bolela hore theko ea lithethefatsi ena e ka ho feletseng ho loketse ka ho bohlokwa ba tsamaiso lona phekolo.

Ha e le go tlhoka mesola ya lithethefatsi ena, bakuli ba hangata e supa ho nako e batlang e telele ea phekolo.