"Azarga" (marotholi a mahlo): litaelo bakeng sa ho sebelisoa, theko, le ulasan pelanggan. Na ho na le leihlo manaka marotholi "Azarga"?

Joang lithethefatsi "Azarga" (leihlo marotholi)? Litaelo ho mokhoa ona, liphello tsa eona tse lehlakoreng, contraindications 'me ho bonahala hore li sebelisoe tla tšohloa sehloohong sena. Ho phaella moo, u tla ithuta ka seo e na le litšobotsi tse diokobatsi ea lithethefatsi sena, kamoo le ka seo dosages lokela ho sebelisoa, ho tla etsahala'ng ka tabeng ea overdose, 'me joalo-joalo.

Foromo ya ho lokolloa ea moo lithethefatsi le sebopeho lona

Foromo se fuoa ho famasi lithethefatsi "Azarga"? Leihlo marotholi - e foromo feela ea ho lokolloa lithethefatsi. 1 di ml moriana na le metsoako e joalo le mafolo-folo e le ka mokgwa wa timolol maleato ka ka tjhelete e ya 5 mg, le brinzolamide (10 mg,).

E lokela ho ile a hlokomela hore "Azarga" o ile a re moriana o akarelletsa ho likarolo thusang. Tsena li akarelletsa mannitol, edetate disodium, hydroxide sodium, sodium chloride, 50% benzalkonium chloride, tyloxapol le metsi a hloekisitsoeng. Ke ka mokhoa oa thekiso e fumaneha "Azarga" lerotholi dropper vial of 5 di ml.

Litšobotsi diokobatsi la marotholi

Seo thepa ha lithethefatsi "Azarga" (leihlo marotholi), thuto eo e leng ka lebokose lebokose hammoho moriana? Joalokaha ho boletsoe ka holimo, moriana o fanoang kenyelletsa ditokiseletso 2 ka sehloohong motsoako a sebetsang. Ho timolol le brinzolamide. Ea bobeli ke sesitisa ea k'habone anhydrase II. Thanks ho eona ka 'mele oa motho liehisa sebopeho sa ions bicarbonate,' me hamorao o ile a fokotswa sodium le ho tsamaisa mokelikeli. Tshebetso ena e etsa hore ea fokotseha ka ea metsi ho hlahisoeng metlae ka ciliary mele oa lekala bonwang. Sena se fella ka theola khatello ea intraocular.

Ha e le timolol, ka nako eo sena ke beta-blocker hore ha e halefisa le tsamaiso ea methapo le kutloelo-bohloko 'me ha e thibela metsoako ea mesifa cardiac. Mora tšebeliso ea moo, ho fokotsa ho thehoe mongobo le eketsa outflow lona.

Pharmacokinetics ya moriana

hore na ba sebelisa lithethefatsi kapa e ananelang, "Azarga" (leihlo marotholi)? Litaelo ho tšobotsi ena e fana ka hore ho sebelisa lihlooho tsa puisano ea likarolo a sebetsang a kang brinzolamide le timolol, ke khona ho phunyeletse ka ajoa systemic. The ntho e qetellang e kena erythrocytes ka mor'a khetha tlamang ho k'habone anhydrase II. mokgatlo lona le liprotheine lero la mali e ka bang 60%.

Brinzolamide metabolized ke O-dealkylation, N-dealkylation le ho kena moea tsa N-propyl lehlakoreng ketane. E ile a fihlela qeto ka liphio foromo sa fetohe ka palo ya 60%. Ka tsela eo 20% tsoa ho 'mele oa motho e le metabolites.

Timolol fire nako e 5 lihora tse ka mor'a ho sebelisa lihlooho tsa puisano tsa moriana. The metabolism tsa ntho e etsahala ka litsela tse peli: ethanolamine ho theha liketane lehlakoreng ka thiadiazole lesale, 'me hape ya ho theha e ethanol lehlakoreng ketane naetrojene tsa morpholine le sehlopha carbonyl eo e amana ho naetrojene e.

Timolol le thehoa metabolites ba excreted haholo-holo ka tsela liphio. About 20% ya lintho tse bonahalang tse di behilwe ka sebōpeho sa fetohe.

Bontšang bakeng sa tshebediso ya chelete

Maemong a mang, lithethefatsi sebelisa "Azarga"? marotholi leihlo ba abeloa ho fokotsa phahameng intraocular khatello, e hlahisoang e loketseng ho bula-angle glaucoma. Hape, ho e atisa ho sebelisoa ka bakuli ba kgatelelo ya madi ocular. Empa sena se ha feela monotherapy e bile lekana ho fokotsa khatello eo.

Contraindications ho tšebeliso ea chelete ea moo

Maemong a mang, u ka se sebelisa lithethefatsi "Azarga" (leihlo marotholi)? Litaelo oa sesebelisoa sena e na le lethathamo ka toka khōlō ea contraindications. Nahana hona joale:

• eketseha nahanela mokuli hore sulfonamides;
• asma, ho akarelletsa le histori;
• Hypersensitivity ho dikarolo ea lithethefatsi;
• obstructive foleng mafu matšoafo, e leng hlaha ka thata haholo;
• hyperchloraemic acidosis;
• bronchial hyperreactivity;
• hypersensitivity ho beta-blockers;
• sinus bradycardia;
• lilemo tsa bana (lilemo tse 18);
• Av-ea le literata II le III lengolo la;
• diabolololo;
• pelo ea ho hloleha (haholo);
• nakong ea bokhachane;
• cardiogenic makala;
• tsoa hong sebelisa inhibitors (molomo), k'habone anhydrase;
• alejiki rhinitis, phallang thata ka ho fetisisa;
• koalo glaucoma;
• matla renal insufficiency.

Seli tebisetsang meriana

Hona joale u tseba, tlas'a bopengwi efe kapa efe e sa kgothaletswa ho sebelisa moriana o, "Azarga". ka kopo ya sesebelisoa tataiso e na le boitsebiso bo mabapi le ho sebetsana le linyeoe ka eo e lokela ho sebelisoa ka hloko haholo. Kenyelelitsoe lethathamong lena, bakuli ba Prinzmetal angina, hyperthyroidism, tlōlo ea e bohareng, pheriferale mafu a ho potoloha ha mali 'me hypotension.

E lokela ho ile a hlokomela hore e le hore ho phekola bakuli ba pseudoexfoliation le pigmentary glaucoma meriana ho noa e lekanyelitsoe. Maemong a joalo, intraocular khatello ea lokela ho leihlo kamehla.

Mehato lokela ho abela lithethefatsi ho bakuli ba itšoare anaphylactic. Ntlha ena ke e loketseng ha e le hantle hore bakuli joalo kamohelo beta-blockers, ba manganga ho dosages ho tloaelehileng ho epinephrine ea ho phekola a itšoare anaphylactic.

Joalokaha ho boletsoe ka holimo, brinzolamide le timolol kgona ho feta systemic absorption. Tabeng ena, ea motsoako pele ka etsa hore liphello tse ho lijana matšoafo tsamaiso, pelo le mali. Tabeng ena, e kgothaletswa ho beha leihlo boemo ba mokuli pele ho 'me nakong kalafo.

Beta-blockers ba beuweng ba hlokolosi feteletseng ka bakuli ba lefu la tsoekere le tšekamelo ea ho ba hypoglycemia. Sena ke ka ntlha ya go ha e le hantle hore chelete tsena ka habonolo pata matšoao a hypoglycemia hlobaetsang.

Pele ho buuoa beta-blockers lokela ho oo tlhomelwa tsoa (bakeng sa matsatsi a 2). Ha e le hantle, nakong ea thethebatso kakaretso, ba khona ho fokotsa myocardial nahanela ho tlhotlheletso (le kutloelo-bohloko), eo e leng ea bohlokoa bakeng sa mosebetsi pelo.

Lithethefatsi "Azarga" eo lekodisisa tla tšohloa mona ka tlase, e na le brinzolamide eo ke sulfonamide. Fuoa hore ho sebelisa lihlooho tsa puisano le hlaha systemic absorption ea moriana o ka, bakuli ba ka 'na bontša liphetoho tse bohloko tse tloaelehileng bakeng sa dintho tsena.

litla-morao

Leihlo marotholi "Azarga", theko ea tsona e phahameng ka ho lekaneng ho ba le e mengata e fapaneng sephara ea litla-morao. Re hlalosa ba ka ho qaqileng le ho feta.

• bakuli Local arabela moriana. Ka 10% ea linyeoe ka bakuli ba tshwaileng e conjunctival hyperemia, corneal khoholeho ea mobu, leihlo omileng, thothofatsang pono, ho teneha tsa litho tsa ditshwantsho tse le boikutlo 'mele e' ngoe. Ka 1% ea bakuli hlokomela punctate keratitis, lero leihlo, alejiki conjunctivitis, itchiness ka leihlo, bohloko leihlo, effusion kenye ka kamoreng e anterior, blepharitis, boemong bo sa thabiseng ka mahlong, crusting ka metshetshe tsa dintshi e, etymology tsa dintshi le leihlo-khatello.
• litla systemic lehlakoreng. Ka 10% ea linyeoe ho na le dysgeusia, 'me 1% - fokotseha ka khatello ea mali, lefu la ho hlobaela, rhinorrhea, obstructive foleng lefu matšoafo, phytoteratology moriri kgolo ya, bohloko oropharynx e, boriba planus, le ho khohlela.

Ho lokela ho hlokomeloe hore e joalo e ntho mafolofolo, tse kang brinzolamide, a ka etsa hore le diphapano latelang: mydriasis, keratitis, eyelid edema, keratopathy, leihlo edema, ho eketseha ha ho epolloa ha methapo ea kutlo optic, subconjunctival cyst, le sekoli ea epithelium corneal, pigmentation sclera, e ile ea eketseha intraocular khatello, sediments ka cornea e, mahlo kulisa, sebopeho sa bokooa corneal, phytoteratology pono, corneal edema, conjunctivitis, e ile ea eketseha lacrimation, ho ruruha ha litsoelesa le meibomian, hypoesthesia leihlo, habeli pono, leihlo omileng okonyunktivit, photophobia, pterygium, fokotseha acuity bonwang le photopsia. Har'a litla systemic lehlakoreng le ka ho hlokomela ho hloka thahasello, ho tepella maikutlo, fokotseha libido, kholofalo memori, litoro tse tšosang, dilenaneo ho se sebetse, somnolence, ho tšoha, amnesia le mafu a ea CNS.

Bakeng sa kalafo ya litla-morao sebelisa tšehetsang le bontshang matshwao phekolo. E lokela ho hang-hang rinsed le mahlo a pholile metsi.

Lithethefatsi "Azarga" (leihlo marotholi): Instructions

Theko ea lithethefatsi ena ka 'na ba e fapaneng, ho itšetlehile ka marangrang famasi. Sebetsa ea lithethefatsi lokela feela ho fetisetswa sebakeng sa heno. Pele tšebeliso, ho vial lokela ho ka matla sisinya.

Ka litekanyetso li behoa ea marotholi "Azarga"? Litaelo ho tšobotsi ena e na le boitsebiso bo qaqileng mabapi le taba ena. Tumellanong le eona e le ea lithethefatsi laolwa lerotholi le leng ka mong le e leihlo conjunctival karaoke tren. Ho phetha mokhoa ona ke ho hotle ho ka makhetlo a mabeli ka letsatsi.

E le hore ho qoba ho ntshetsopele ya litla systemic lehlakoreng ka mor'a ho sebelisa lithethefatsi e kgothaletswa ho khanya monoana khatello ea kelello k'honeng ea leihlo (sebakeng boqapi ba karaoke tren lacrimal). Joalo tšebetso e lokela ho ba teng ka bakeng sa metsotso e bonyane ba babeli. Sena se haholo fokotsa systemic absorption ho bolela.

Haeba ho sebelisoa ha meriana e se e hloloheloa, kalafo lokela ho tsoela pele ka nako e behiloeng ka lethal dose hlahlamang. Ha lethal dose ona tabeng leha e le efe lokela ho sa feteng lerotholi le leng ka mong le e karaoke tren conjunctival habeli ka letsatsi.

Boemong bo joalo, haeba ngaka nkeloa sebaka e le glaucoma ea lithethefatsi meriana "Azarga", e kgothaletswa ho sebelisa feela letsatsi le hlahlamang.

overdose

Jwale tlhahisoleseding efe kapa efe ka maemo a ho overdose di tlalehile. Leha ho le joalo, maemong a joalo, ho na le kgonego ya litla eketsehileng lehlakoreng.

Lemosa ha ba sebelisa lithethefatsi, ulasan pelanggan

makgetheng seo ba le leihlo marotholi "Azarga"? Bakuli ba maikutlo ka tsona ke sa hlakang haholo. Ka mohlala, ka batho ba hōlileng inhibitors k'habone anhydrase, tse sebediswa ka molomo, e se eka ka ho toba ama bokhoni ba ho ikemisetsa mosebetsi eo hloka tšebelisano e se e eketsehile kapa hloko. e le hantle ena e lokela ho ho nkoa ka ka ho nahanela ha abela lithethefatsi ho lingaka.

Ka tšebeliso ea lihlooho tsa puisano tsa moriana ka bakuli ba aparang le lilense ikopanye le, ho ke ke ho hlokahala hore ho hlokomela boemo ba cornea ena. Sena ke ka ntlha ya go ha e le hantle hore hangata k'habone anhydrase inhibitors lebisa qhala hydration tsa lona. Pele ho sebelisa lense e bolela kgothaletswa ho tlosa. Kenya ba khutlisetsa desirably sa pele ho moo ho feta ¼ hora ka mora tšebeliso ea lithethefatsi ka.

E sa kgothaletswa ho ama ntlha ea bottle ka holimo efe kapa efe. Ho seng joalo ho ka 'na etsahala silafatsoa. Ka mor'a ho sebelisa meriana dropper lokela ho hang-hang koala.

Sebelisana le lithethefatsi tse ling

Bokae leihlo marotholi "Azarga"? theko ea bona e haholo phahameng. Ba bang ba famasi liketane joalo ho lokisetsa bakeng sa kopo ea lihlooho tsa puisano li ka rekoa ka 950-1050 li-ruble Serussia.

Le ho sebelisa tsoa hong ea lithethefatsi ka molomo inhibitors k'habone anhydrase (mohlala, lithethefatsi "Diakarb", "Sulfadiurin", "Fonurit", "Glaupaks", "Dilamoks" joalo-joalo.) E se eka ho eketsa liphello systemic lehlakoreng.

Ba hlokolosi feteletseng kopana sesebelisoa sena ka troleandomycin, ketoconazole, ritonavir, itraconazole le clotrimazole.

Ho na le ke le monyetla ho rua ho hypotensive bohato le deceleration ba otla ha pelo holim 'a fumana e elements a sebetsang a - timolol - le k'halsiamo blockers le kanaleng (mohlala, lithethefatsi "Verapamil," "Amlodipine" "Diltiazem", joalo-joalo.), Beta-blockers, guanethidine, parasympathomimetics, cardiac glycosides le mahlahana a bakeng sa kalafo ya arrhythmias cardiac.

Ho fokotseha ha ho otla ha pelo hlokomela le ho sebelisa tsoa hong ea dintho quinidine kapa cimetidine.

Analoge eyedrops "Azarga"

Hoo e batlang e lithethefatsi tsohle na analogues bona. Sena se etsa hore ho ka khoneha a se ke a ba khaotse ho phekoloa ha lefu jaana esita le ka ho ba sieo ha meriana e balletsweng ke ngaka.

Kahoo ke seo 'manaka tsa "Azarga" leihlo marotholi ke molemo ka ho fetisisa? A karabo e hlakileng ea potso ena e thata haholo. Ka mor'a hore tsohle, lithethefatsi tse tšoanang tse ntle ka tsela ea bona. Ho feta moo, ba ka 'na ba le e fapaneng ka ho feletseng liphello tse le contraindications. Ka hona, pele ho sebelisa bona, etsa bonnete ba ho buisana le ngaka ea hao.

Joale ho se etsa ha mokuli a se a sa khone ho reka leihlo marotholi "Azarga"? E manaka oa sesebelisoa sena ka kamehla fumanoa famasi ena. Ho etsa sena, o lokela ho feela hopola lebitso la hae.

Kahoo, e manaka ea lithethefatsi e akarelletsa meriana latelang (leihlo marotholi):

• "Teva-Timolol".
• "Oftan timolol."
• "Inderal".
• "Duoprost".
• "Arutimol".
• "The EU Betalmik".
• "Timolol bufus".
• "Timadren".
• "Betoptik".
• "Timolol-Akos".
• "Betoptik C".
• "Timolol-dia."
• "Betoftan".
• "Timolol-lense".
• "Ganfort".
• "Timolol-Betalek".
• "Glautam".
• "Timolol-motse".
• "DuoTrav."

lithethefatsi life tse ling tseo nka sebaka sa lithethefatsi "Azarga"? E manaka oa sesebelisoa sa lokela ho hakaalo kenyeletsa e tšoanang metsoako mafolofolo ka boeona. Har'a lithethefatsi tse joalo ke tse latelang:

• "Timolol".
• "Betaxolol."
• "Timolol-MEZ".
• "Okupres-E."
• "Kombigan".
• "Okumol".
• "Ksalakom".
• "TimoGeksal".
• Leihlo Gel "Oftan Timogel".
• "Ksonef".
• "Optibetol".
• "Niolol" leihlo gel.
• "Ksonef BC".
• "Timolollong".
• "Okuker";
• Leihlo marotholi ntle o bolokang "timolol-motse".
• "Okumed" joalo-joalo.